Home Products Antibodies Primary Antibodies N254530PEC7
N254530PEC7

Desmoglein-2 Antibody (6D8), PE/Cy7, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N254530PEC7-Each-of-1 In Stock ₹ 60,448.14

N254530PEC7 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

Desmoglein-2

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

DSG2

Immunogen

Recombinant human Desmoglein-2 protein (Uniprot: Q14126)

Quantity

0.1 mL

Gene ID (Entrez)

1829.0

Target Species

Human

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

6D8

Dilution

Flow Cytometry

Gene Alias

ARVC10, ARVD10, Cadherin family member 5, CDHF5MGC117034, CMD1BB, desmoglein 2, desmoglein-2, HDGC, MGC117036, MGC117037

Host Species

Mouse

Purification Method

Protein A or G purified

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 165kDa, identified as Desmoglein-2 (DSG2). This monoclonal antibody recognizes the extracellular domain of human desmoglein-2. Desmoglein-2 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cyto

Content And Storage

Store at 4°C in the dark. Do not freeze.

Description

  • Desmoglein-2 Monoclonal specifically detects Desmoglein-2 in Human samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N254530PEC7

--

Antigen:
Desmoglein-2
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
DSG2
Immunogen:
Recombinant human Desmoglein-2 protein (Uniprot: Q14126)
Quantity:
0.1 mL
Gene ID (Entrez):
1829.0
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
6D8
Dilution:
Flow Cytometry
Gene Alias:
ARVC10, ARVD10, Cadherin family member 5, CDHF5MGC117034, CMD1BB, desmoglein 2, desmoglein-2, HDGC, MGC117036, MGC117037
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 165kDa, identified as Desmoglein-2 (DSG2). This monoclonal antibody recognizes the extracellular domain of human desmoglein-2. Desmoglein-2 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cyto
Content And Storage:
Store at 4°C in the dark. Do not freeze.

Img

Novus Biologicals

N254535PEC5

--

Antigen:
P-Cadherin
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CDH3
Immunogen:
Recombinant human P-Cadherin protein (Uniprot: P22223)
Quantity:
0.1 mL
Gene ID (Entrez):
1001.0
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
12H6
Dilution:
Flow Cytometry
Gene Alias:
cadherin 3, P-cadherin (placental), cadherin 3, type 1, P-cadherin (placental), cadherin-3, CDHPcalcium-dependent adhesion protein, placental, HJMD, PCADP-cadherin, Placental cadherin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark. Do not freeze.

Img

Novus Biologicals

N254535PEC7

--

Antigen:
P-Cadherin
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CDH3
Immunogen:
Recombinant human P-Cadherin protein (Uniprot: P22223)
Quantity:
0.1 mL
Gene ID (Entrez):
1001.0
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
12H6
Dilution:
Flow Cytometry
Gene Alias:
cadherin 3, P-cadherin (placental), cadherin 3, type 1, P-cadherin (placental), cadherin-3, CDHPcalcium-dependent adhesion protein, placental, HJMD, PCADP-cadherin, Placental cadherin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark. Do not freeze.

Img

Novus Biologicals

N254548APC7

--

Antigen:
CD81
Classification:
Monoclonal
Conjugate:
APC-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CD81
Immunogen:
Recombinant full-length human CD81 protein (Uniprot: P60033)
Quantity:
0.1 mL
Gene ID (Entrez):
975.0
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunoassay
Clone:
1.3.3.22
Dilution:
Flow Cytometry, Flow (Cell Surface), Knockout Validated
Gene Alias:
CD81 antigen, CD81 antigen (target of antiproliferative 1), CD81 molecule, CVID6, TAPA1, TAPA-1, Target of the antiproliferative 1, Tetraspanin-28, Tspan-28, tspan-28,26 kDa cell surface protein TAPA-1, TSPAN28S5.7
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
Content And Storage:
Store at 4°C in the dark. Do not freeze.