NB005897

Carbonic Anhydrase IX/CA9 Antibody (SPM314), FITC, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB005897-Each-of-1 In Stock ₹ 55,271.76

NB005897 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Carbonic Anhydrase IX/CA9

Classification

Monoclonal

Conjugate

FITC

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

CA9

Immunogen

Microsomal fraction of human renal cortical tissue homogenate was used to develop this Carbonic Anhydrase IX/CA9 Antibody (SPM314).

Quantity

0.1 mL

Research Discipline

Cancer, HIF Target Genes, Hypoxia, Lipid and Metabolism, Metastasis, Renal Cell Carcinoma Cell Markers

Test Specificity

Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowmans capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This monoclonal antibody may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

SPM314

Dilution

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias

CAIX, CA-IX, Carbonate dehydratase IX, carbonic anhydrase 9, carbonic anhydrase IX, carbonic dehydratase, EC 4.2.1.1, G250, Membrane antigen MN, MN, P54/58N, PMW1, RCC-associated antigen G250, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Equine

Isotype

IgG2b κ

Related Products

Img

Novus Biologicals

NB005910

--

Img

Novus Biologicals

NB005912

--

Img

Novus Biologicals

NB006770

--

Img

Novus Biologicals

NB006203

--

Img

Novus Biologicals

NB006765

--

Img

Novus Biologicals

NB006766

--

Img

Novus Biologicals

NB006767

--

Img

Novus Biologicals

NB006733

--

Description

  • Carbonic Anhydrase IX/CA9 Monoclonal specifically detects Carbonic Anhydrase IX/CA9 in Human, Equine samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB005897

--


Antigen:
Carbonic Anhydrase IX/CA9

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CA9

Immunogen:
Microsomal fraction of human renal cortical tissue homogenate was used to develop this Carbonic Anhydrase IX/CA9 Antibody (SPM314).

Quantity:
0.1 mL

Research Discipline:
Cancer, HIF Target Genes, Hypoxia, Lipid and Metabolism, Metastasis, Renal Cell Carcinoma Cell Markers

Test Specificity:
Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowmans capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This monoclonal antibody may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM314

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CAIX, CA-IX, Carbonate dehydratase IX, carbonic anhydrase 9, carbonic anhydrase IX, carbonic dehydratase, EC 4.2.1.1, G250, Membrane antigen MN, MN, P54/58N, PMW1, RCC-associated antigen G250, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Equine

Isotype:
IgG2b κ

Img

Novus Biologicals

NB005904

--


Antigen:
RBP4/Retinol-Binding Protein 4

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
RBP4

Immunogen:
Retinol binding protein purified from human plasma

Quantity:
0.1 mL

Research Discipline:
Cancer, Diabetes Research, Lipid and Metabolism

Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM442

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Goat, Primate, Rabbit

Isotype:
IgG1 κ

Img

Novus Biologicals

NB005905

--


Antigen:
RBP4/Retinol-Binding Protein 4

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
RBP4

Immunogen:
Retinol binding protein purified from human plasma

Quantity:
0.1 mL

Research Discipline:
Cancer, Diabetes Research, Lipid and Metabolism

Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM442

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Goat, Primate, Rabbit

Isotype:
IgG1 κ

Img

Novus Biologicals

NB005906

--


Antigen:
RBP4/Retinol-Binding Protein 4

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
RBP4

Immunogen:
Retinol binding protein purified from human plasma

Quantity:
0.1 mL

Research Discipline:
Cancer, Diabetes Research, Lipid and Metabolism

Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM442

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Goat, Primate, Rabbit

Isotype:
IgG1 κ