NB006021
Progesterone R/NR3C3 Antibody (SPM566), DyLight 594, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB006021-Each-of-1 | In Stock | ₹ 53,688.90 |
NB006021 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,688.90
GST (18%): ₹ 9,664.002
Total Price: ₹ 63,352.902
Antigen
Progesterone R/NR3C3
Classification
Monoclonal
Conjugate
DyLight 594
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
PGR
Immunogen
Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
Quantity
0.1 mL
Research Discipline
Breast Cancer, Cancer, Phospho Specific
Test Specificity
This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone
SPM566
Dilution
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias
NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: Progesterone R/NR3C3
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: PGR
Immunogen: Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
Quantity: 0.1 mL
Research Discipline: Breast Cancer, Cancer, Phospho Specific
Test Specificity: This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: SPM566
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 κ
Antigen:
Progesterone R/NR3C3
Classification:
Monoclonal
Conjugate:
DyLight 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
PGR
Immunogen:
Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
Quantity:
0.1 mL
Research Discipline:
Breast Cancer, Cancer, Phospho Specific
Test Specificity:
This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM566
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Progesterone R/NR3C3
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: PGR
Immunogen: Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
Quantity: 0.1 mL
Research Discipline: Breast Cancer, Cancer, Phospho Specific
Test Specificity: This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Content And Storage: Store at 4°C in the dark.
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: SPM566
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 κ
Antigen:
Progesterone R/NR3C3
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
PGR
Immunogen:
Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
Quantity:
0.1 mL
Research Discipline:
Breast Cancer, Cancer, Phospho Specific
Test Specificity:
This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Content And Storage:
Store at 4°C in the dark.
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM566
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 κ
Antigen: SUMO2/3
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: SUMO2
Immunogen: Recombinant human SUMO2 protein
Quantity: 0.1 mL
Research Discipline: Apoptosis
Test Specificity: This monoclonal antibody reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM572
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: HSMT3, small ubiquitin-like modifier 2, SMT3A, SMT3B, SMT3H2, SUMO2, SUMO3
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 κ
Antigen:
SUMO2/3
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
SUMO2
Immunogen:
Recombinant human SUMO2 protein
Quantity:
0.1 mL
Research Discipline:
Apoptosis
Test Specificity:
This monoclonal antibody reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM572
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
HSMT3, small ubiquitin-like modifier 2, SMT3A, SMT3B, SMT3H2, SUMO2, SUMO3
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 κ
Antigen: SUMO2/3
Classification: Monoclonal
Conjugate: Alexa Fluor 750
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: SUMO2
Immunogen: Recombinant human SUMO2 protein
Quantity: 0.1 mL
Research Discipline: Apoptosis
Test Specificity: This monoclonal antibody reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimers disease.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM572
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: HSMT3, small ubiquitin-like modifier 2, SMT3A, SMT3B, SMT3H2, SUMO2, SUMO3
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 κ
Antigen:
SUMO2/3
Classification:
Monoclonal
Conjugate:
Alexa Fluor 750
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
SUMO2
Immunogen:
Recombinant human SUMO2 protein
Quantity:
0.1 mL
Research Discipline:
Apoptosis
Test Specificity:
This monoclonal antibody reacts with both SUMO-2 and SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates beta-Amyloid generation and may be critical in the onset or progression of Alzheimers disease.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM572
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
HSMT3, small ubiquitin-like modifier 2, SMT3A, SMT3B, SMT3H2, SUMO2, SUMO3
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 κ