FoxP3 Antibody (SPM579), Alexa Fluor™ 594, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB006035-Each-of-1 | In Stock | ₹ 56,555.16 |
NB006035 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,555.16
GST (18%): ₹ 10,179.929
Total Price: ₹ 66,735.089
Antigen
FoxP3
Classification
Monoclonal
Conjugate
Alexa Fluor 594
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
FOXP3
Immunogen
Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Quantity
0.1 mL
Research Discipline
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Regulatory Immunology, Transcription Factors and Regulators
Test Specificity
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage
Store at 4°C in the dark.
Applications
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone
SPM579
Dilution
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Primate
Isotype
IgG1 κ
Related Products
Description
- FoxP3 Monoclonal specifically detects FoxP3 in Human, Mouse, Monkey samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: FoxP3
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: FOXP3
Immunogen: Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Quantity: 0.1 mL
Research Discipline: Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Regulatory Immunology, Transcription Factors and Regulators
Test Specificity: Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone: SPM579
Dilution: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias: AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Primate
Isotype: IgG1 κ
Antigen: FoxP3
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: FOXP3
Immunogen: Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Quantity: 0.1 mL
Research Discipline: Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Regulatory Immunology, Transcription Factors and Regulators
Test Specificity: Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone: SPM579
Dilution: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias: AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Primate
Isotype: IgG1 κ
Antigen: Cytokeratin, pan
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: KRT1
Immunogen: This Cytokeratin, pan Antibody (SPM583) was developed against keratin-enriched preparation from cultured human A431 cells.
Quantity: 0.1 mL
Research Discipline: Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
Test Specificity: This monoclonal antibody recognizes cytokeratin 4, 5, 6, 8, 10, 13, and 18. This is a broad-spectrum antibody which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM583
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: __
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Primate
Isotype: IgG1 κ