NB006134

EMMPRIN/CD147 Antibody (8D6), FITC, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB006134-Each-of-1 In Stock ₹ 55,271.76

NB006134 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

EMMPRIN/CD147

Classification

Monoclonal

Conjugate

FITC

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

BSG

Immunogen

Human T cell line Molt 13

Quantity

0.1 mL

Research Discipline

Cancer, Signal Transduction, Vision

Test Specificity

This monoclonal antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

8D6

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias

5F7, basigin, basigin (Ok blood group), CD147, CD147 antigen, Collagenase stimulatory factor, EMMPRINTCSF, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, M6, OK, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG1 κ

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Description

  • EMMPRIN/CD147 Monoclonal specifically detects EMMPRIN/CD147 in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NB006134

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Antigen:
EMMPRIN/CD147

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
BSG

Immunogen:
Human T cell line Molt 13

Quantity:
0.1 mL

Research Discipline:
Cancer, Signal Transduction, Vision

Test Specificity:
This monoclonal antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
8D6

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
5F7, basigin, basigin (Ok blood group), CD147, CD147 antigen, Collagenase stimulatory factor, EMMPRINTCSF, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, M6, OK, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB006136

--


Antigen:
Melan-A/MART-1

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MLANA

Immunogen:
Recombinant full-length hMelan-A/MART-1 protein (A103; M2-7C10; M2-9E3) (Uniprot: Q16655)

Quantity:
0.1 mL

Research Discipline:
Cell Biology, Cellular Markers, Immunology

Test Specificity:
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody cocktail labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
A103 + M2-7C10 + M2-9E3

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)

Gene Alias:
Antigen LB39-AA, Antigen SK29-AA, Mart 1 Melan A, MART1MART-1, melan-A, melanoma antigen recognized by T-cells 1, Protein Melan-A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Canine

Isotype:
IgG1 κ, IgG2b λ, IgG2b κ

Img

Novus Biologicals

NB006137

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Antigen:
Melanoma Marker (MART-1 + Tyrosinase + gp100)

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
__

Immunogen:
Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Quantity:
0.1 mL

Research Discipline:
__

Test Specificity:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
A103 + T311 + HMB45

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
MART1, MART-1, melan-A, MLANA

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1, IgG2a κ

Img

Novus Biologicals

NB006138

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Antigen:
Cytokeratin 19

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
KRT19

Immunogen:
Human breast cancer MCF-7 cells (A53-B/A2); Human mammary epithelial organoids (BA17)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Neuroscience, Stem Cell Markers

Test Specificity:
This monoclonal antibody reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
A53-B/A2.26 + BA17

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
40-kDa keratin intermediate filament, CK19, CK-19, cytokeratin 19, K19, K1CS, keratin 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, Keratin-19, MGC15366

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2a λ, IgG1 κ