NB006842

SUMO1 Antibody (SPM571), FITC, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB006842-Each-of-1 In Stock ₹ 55,271.76

NB006842 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

SUMO1

Classification

Monoclonal

Conjugate

FITC

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

SUMO1

Immunogen

Recombinant human SUMO1 protein (Uniprot: P63165)

Quantity

0.1 mL

Research Discipline

Alzheimers Research, Core ESC Like Genes, Neuroscience, Stem Cell Markers

Test Specificity

This monoclonal antibody is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

SPM571

Dilution

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias

DAP1, GAP modifying protein 1, GAP-modifying protein 1, GMP1SMT3CSMT3H3OFC10UBL1PIC1, SENP2, sentrin, small ubiquitin-related modifier 1, SMT3, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), SMT3 suppressor of mif two 3 homolog 1 (yeast), Smt3C, SUMO-1, Ubiquitin-homology domain protein PIC1, ubiquitin-like 1 (sentrin), Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG1 κ

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Description

  • SUMO1 Monoclonal specifically detects SUMO1 in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB006842

--


Antigen:
SUMO1

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
SUMO1

Immunogen:
Recombinant human SUMO1 protein (Uniprot: P63165)

Quantity:
0.1 mL

Research Discipline:
Alzheimers Research, Core ESC Like Genes, Neuroscience, Stem Cell Markers

Test Specificity:
This monoclonal antibody is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM571

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
DAP1, GAP modifying protein 1, GAP-modifying protein 1, GMP1SMT3CSMT3H3OFC10UBL1PIC1, SENP2, sentrin, small ubiquitin-related modifier 1, SMT3, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), SMT3 suppressor of mif two 3 homolog 1 (yeast), Smt3C, SUMO-1, Ubiquitin-homology domain protein PIC1, ubiquitin-like 1 (sentrin), Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB006843

--


Antigen:
TFF1/pS2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
TFF1

Immunogen:
Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human TFF1/pS2. (Uniprot: P04155)

Quantity:
0.1 mL

Research Discipline:
Breast Cancer, Cancer

Test Specificity:
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM573

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
BCEIbreast cancer, estrogen-inducible sequence expressed in, Breast cancer estrogen-inducible protein, breast cancer estrogen-inducible sequence, D21S21, gastrointestinal trefoil protein pS2, hP1.A, HPS2, pNR-2, Polypeptide P1.A, Protein pS2, pS2, trefoil factor 1, trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Primate

Isotype:
IgG1 κ

Img

Novus Biologicals

NB006845

--


Antigen:
TFF1/pS2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
TFF1

Immunogen:
Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human TFF1/pS2. (Uniprot: P04155)

Quantity:
0.1 mL

Research Discipline:
Breast Cancer, Cancer

Test Specificity:
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM573

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
BCEIbreast cancer, estrogen-inducible sequence expressed in, Breast cancer estrogen-inducible protein, breast cancer estrogen-inducible sequence, D21S21, gastrointestinal trefoil protein pS2, hP1.A, HPS2, pNR-2, Polypeptide P1.A, Protein pS2, pS2, trefoil factor 1, trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Primate

Isotype:
IgG1 κ

Img

Novus Biologicals

NB006846

--


Antigen:
TFF1/pS2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
TFF1

Immunogen:
Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human TFF1/pS2. (Uniprot: P04155)

Quantity:
0.1 mL

Research Discipline:
Breast Cancer, Cancer

Test Specificity:
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM573

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
BCEIbreast cancer, estrogen-inducible sequence expressed in, Breast cancer estrogen-inducible protein, breast cancer estrogen-inducible sequence, D21S21, gastrointestinal trefoil protein pS2, hP1.A, HPS2, pNR-2, Polypeptide P1.A, Protein pS2, pS2, trefoil factor 1, trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Primate

Isotype:
IgG1 κ