NB007503
CPS1 Antibody (SPM615), DyLight 594, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB007503-Each-of-1 | In Stock | ₹ 53,688.90 |
NB007503 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,688.90
GST (18%): ₹ 9,664.002
Total Price: ₹ 63,352.902
Antigen
CPS1
Classification
Monoclonal
Conjugate
DyLight 594
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
CPS1
Immunogen
Recombinant human CPS1 protein (Uniprot: P31327)
Quantity
0.1 mL
Primary or Secondary
Primary
Target Species
Human, Canine
Isotype
IgG1 κ
Applications
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
SPM615
Dilution
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias
carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Test Specificity
This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage
Store at 4°C in the dark.
Related Products
Description
- CPS1 Monoclonal specifically detects CPS1 in Human, Canine samples
- It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.
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Antigen: CPS1
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CPS1
Immunogen: Recombinant human CPS1 protein (Uniprot: P31327)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human, Canine
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM615
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage: Store at 4°C in the dark.
Antigen:
CPS1
Classification:
Monoclonal
Conjugate:
DyLight 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
CPS1
Immunogen:
Recombinant human CPS1 protein (Uniprot: P31327)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human, Canine
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM615
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage:
Store at 4°C in the dark.
Antigen: CD34
Classification: Monoclonal
Conjugate: Alexa Fluor 405
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CD34
Immunogen: Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 λ
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: QBEnd/10 + HPCA1/763
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Content And Storage: Store at 4°C in the dark.
Antigen:
CD34
Classification:
Monoclonal
Conjugate:
Alexa Fluor 405
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
CD34
Immunogen:
Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 λ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
QBEnd/10 + HPCA1/763
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Content And Storage:
Store at 4°C in the dark.
Antigen: CD34
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CD34
Immunogen: Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 λ
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: QBEnd/10 + HPCA1/763
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Content And Storage: Store at 4°C in the dark.
Antigen:
CD34
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
CD34
Immunogen:
Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 λ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
QBEnd/10 + HPCA1/763
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Content And Storage:
Store at 4°C in the dark.
Antigen: CD34
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CD34
Immunogen: Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 λ
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: QBEnd/10 + HPCA1/763
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Content And Storage: Store at 4°C in the dark.
Antigen:
CD34
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
CD34
Immunogen:
Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 λ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
QBEnd/10 + HPCA1/763
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Content And Storage:
Store at 4°C in the dark.