CD11c Antibody (ITGAX/1243), DyLight 488, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB008219-Each-of-1 | In Stock | ₹ 56,298.48 |
NB008219 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,298.48
GST (18%): ₹ 10,133.726
Total Price: ₹ 66,432.206
Antigen
CD11c
Classification
Monoclonal
Conjugate
DyLight 488
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
ITGAX
Immunogen
Recombinant fragment (aa 637-827) of human CD11c protein (exact sequence is proprietary) (Uniprot: P20702)
Quantity
0.1 mL
Research Discipline
Dendritic Cell Markers, Signal Transduction
Test Specificity
Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Content And Storage
Store at 4°C in the dark.
Applications
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
ITGAX/1243
Dilution
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias
95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG2b κ
Related Products
Description
- CD11c Monoclonal specifically detects CD11c in Human samples
- It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: CD11c
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: ITGAX
Immunogen: Recombinant fragment (aa 637-827) of human CD11c protein (exact sequence is proprietary) (Uniprot: P20702)
Quantity: 0.1 mL
Research Discipline: Dendritic Cell Markers, Signal Transduction
Test Specificity: Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: ITGAX/1243
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: 95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ
Antigen: PTH
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: PTH
Immunogen: A synthetic peptide around amino acids 1-34 of human mature-PTH-polypeptide (exact sequence is proprietary) (Uniprot: P01270)
Quantity: 0.1 mL
Research Discipline: Apoptosis, Biologically Active Proteins, Cancer
Test Specificity: Epitope of this monoclonal antibody maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: PTH/911
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ
Antigen: PTH
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: PTH
Immunogen: A synthetic peptide around aa 1-34 of human mature-PTH-polypeptide (exact sequence is proprietary) (Uniprot: P01270)
Quantity: 0.1 mL
Research Discipline: Apoptosis, Biologically Active Proteins, Cancer
Test Specificity: Epitope of this monoclonal antibody maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM604
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ
