NB008263

B220/CD45R Antibody (PTPRC/1461), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB008263-Each-of-1 In Stock ₹ 55,271.76

NB008263 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

B220/CD45R

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

PTPRC

Immunogen

Human B-lymphocytes (Uniprot: P08575)

Quantity

0.1 mL

Research Discipline

Adaptive Immunity, Cell Biology, Cellular Markers, Cellular Signaling, Cytokine Research, Glia Markers, Hematopoietic Stem Cell Markers, Immunology, MAP Kinase Signaling, Mast Cell Markers, Mesenchymal Stem Cell Markers, Microglia Markers, Modulation of DNA Pools, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

Test Specificity

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

PTPRC/1461

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG2a κ

Related Products

Img

Novus Biologicals

NB152227

--

Img

Novus Biologicals

NB152243

--

Img

Novus Biologicals

NB152246

--

Img

Novus Biologicals

NB152236

--

Img

Novus Biologicals

NB152238

--

Img

Novus Biologicals

NB152230

--

Img

Novus Biologicals

NB152231

--

Img

Novus Biologicals

NB10065018R

--

Description

  • B220/CD45R Monoclonal specifically detects B220/CD45R in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB008263

--


Antigen:
B220/CD45R

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
PTPRC

Immunogen:
Human B-lymphocytes (Uniprot: P08575)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Cellular Markers, Cellular Signaling, Cytokine Research, Glia Markers, Hematopoietic Stem Cell Markers, Immunology, MAP Kinase Signaling, Mast Cell Markers, Mesenchymal Stem Cell Markers, Microglia Markers, Modulation of DNA Pools, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

Test Specificity:
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
PTPRC/1461

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2a κ

Img

Novus Biologicals

NB008267

--


Antigen:
Glypican 3

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
GPC3

Immunogen:
Recombinant human full-length Glypican 3 protein (Uniprot: P51654)

Quantity:
0.1 mL

Research Discipline:
__

Test Specificity:
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
GPC3/1534R

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Isotype:
IgG

Img

Novus Biologicals

NB008269

--


Antigen:
Glypican 3

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
GPC3

Immunogen:
Recombinant human full-length Glypican 3 protein (Uniprot: P51654)

Quantity:
0.1 mL

Research Discipline:
__

Test Specificity:
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
GPC3/1534R

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Isotype:
IgG

Img

Novus Biologicals

NB008270

--


Antigen:
Glypican 3

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
GPC3

Immunogen:
Recombinant human full-length Glypican 3 protein (Uniprot: P51654)

Quantity:
0.1 mL

Research Discipline:
__

Test Specificity:
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
GPC3/1534R

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Isotype:
IgG