NB008358
TIMP-2 Antibody (3A4), DyLight 594, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB008358-Each-of-1 | In Stock | ₹ 55,271.76 |
NB008358 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
TIMP-2
Classification
Monoclonal
Conjugate
DyLight 594
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
TIMP2
Immunogen
A synthetic peptide from the N-terminus of human TIMP-2 protein (aa56-66) (DSGNDIYGNPI) (Uniprot: P16035)
Quantity
0.1 mL
Research Discipline
Angiogenesis, Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers
Test Specificity
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
3A4
Dilution
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias
CSC-21Ktissue inhibitor of metalloproteinase 2, metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish
Isotype
IgG2a κ
Related Products
Description
- TIMP-2 Monoclonal specifically detects TIMP-2 in Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: TIMP-2
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: TIMP2
Immunogen: A synthetic peptide from the N-terminus of human TIMP-2 protein (aa56-66) (DSGNDIYGNPI) (Uniprot: P16035)
Quantity: 0.1 mL
Research Discipline: Angiogenesis, Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers
Test Specificity: It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 3A4
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: CSC-21Ktissue inhibitor of metalloproteinase 2, metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish
Isotype: IgG2a κ
Antigen:
TIMP-2
Classification:
Monoclonal
Conjugate:
DyLight 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
TIMP2
Immunogen:
A synthetic peptide from the N-terminus of human TIMP-2 protein (aa56-66) (DSGNDIYGNPI) (Uniprot: P16035)
Quantity:
0.1 mL
Research Discipline:
Angiogenesis, Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers
Test Specificity:
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
3A4
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
CSC-21Ktissue inhibitor of metalloproteinase 2, metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish
Isotype:
IgG2a κ
Antigen: CD30/TNFRSF8
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: TNFRSF8
Immunogen: Recombinant human full-length CD30/TNFRSF8 protein (Uniprot: P28908)
Quantity: 0.1 mL
Research Discipline: Apoptosis, B Cell Development and Differentiation Markers, Cell Cycle and Replication, Immunology, Stem Cell Markers
Test Specificity: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This monoclonal antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: Ki-1/1747R
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species: Rabbit
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Antigen:
CD30/TNFRSF8
Classification:
Monoclonal
Conjugate:
DyLight 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
TNFRSF8
Immunogen:
Recombinant human full-length CD30/TNFRSF8 protein (Uniprot: P28908)
Quantity:
0.1 mL
Research Discipline:
Apoptosis, B Cell Development and Differentiation Markers, Cell Cycle and Replication, Immunology, Stem Cell Markers
Test Specificity:
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This monoclonal antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
Ki-1/1747R
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species:
Rabbit
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG
Antigen: S100B
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: S100B
Immunogen: Purified bovine brain S100 protein (4C4.9); Recombinant full-length human S100B protein (S100B/1012) (Uniprot: P04271)
Quantity: 0.1 mL
Research Discipline: Alzheimers Research, Apoptosis, Biologically Active Proteins, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Epigenetics, Hypoxia, Lipid and Metabolism, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Peroxisome Markers, Signal Transduction, Stem Cells
Test Specificity: S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 4C4.9 + S100B/1012
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: beta (neural), NEF, S100, S100 beta, S100 calcium binding protein B, S100 calcium-binding protein B, S100 calcium-binding protein, beta (neural), S-100 calcium-binding protein, beta chain, 10protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100beta
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Bovine
Isotype: IgG2a κ
Antigen:
S100B
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
S100B
Immunogen:
Purified bovine brain S100 protein (4C4.9); Recombinant full-length human S100B protein (S100B/1012) (Uniprot: P04271)
Quantity:
0.1 mL
Research Discipline:
Alzheimers Research, Apoptosis, Biologically Active Proteins, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Epigenetics, Hypoxia, Lipid and Metabolism, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Peroxisome Markers, Signal Transduction, Stem Cells
Test Specificity:
S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
4C4.9 + S100B/1012
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
beta (neural), NEF, S100, S100 beta, S100 calcium binding protein B, S100 calcium-binding protein B, S100 calcium-binding protein, beta (neural), S-100 calcium-binding protein, beta chain, 10protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100beta
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Bovine
Isotype:
IgG2a κ
Antigen: Integrin beta 3/CD61
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: ITGB3
Immunogen: Recombinant human Integrin beta 3/CD61 protein (Uniprot: P05106)
Quantity: 0.1 mL
Research Discipline: Angiogenesis, Cancer, Cell Biology, Cellular Markers, Extracellular Matrix, Immunology, Phospho Specific, Signal Transduction, Stem Cell Markers
Test Specificity: Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: ITGB3/1713
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: CD61, CD61 antigen, GP3Aplatelet glycoprotein IIIa, GPIIIaintegrin beta-3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITG B3, Platelet membrane glycoprotein IIIa
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 κ
Antigen:
Integrin beta 3/CD61
Classification:
Monoclonal
Conjugate:
DyLight 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
ITGB3
Immunogen:
Recombinant human Integrin beta 3/CD61 protein (Uniprot: P05106)
Quantity:
0.1 mL
Research Discipline:
Angiogenesis, Cancer, Cell Biology, Cellular Markers, Extracellular Matrix, Immunology, Phospho Specific, Signal Transduction, Stem Cell Markers
Test Specificity:
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
ITGB3/1713
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
CD61, CD61 antigen, GP3Aplatelet glycoprotein IIIa, GPIIIaintegrin beta-3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITG B3, Platelet membrane glycoprotein IIIa
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 κ