NB008809

TROP-2 Antibody (TACSTD2/2152), DyLight 550, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB008809-Each-of-1 In Stock ₹ 55,271.76

NB008809 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

TROP-2

Classification

Monoclonal

Conjugate

DyLight 550

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

TACSTD2

Immunogen

Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )

Quantity

0.1 mL

Research Discipline

Signal Transduction

Test Specificity

TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

TACSTD2/2152

Dilution

Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG1 κ

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Description

  • TROP-2 Monoclonal specifically detects TROP-2 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB008809

--


Antigen:
TROP-2

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
TACSTD2

Immunogen:
Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )

Quantity:
0.1 mL

Research Discipline:
Signal Transduction

Test Specificity:
TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
TACSTD2/2152

Dilution:
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB008812

--


Antigen:
Bcl-6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL6

Immunogen:
Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Tumor Suppressors

Test Specificity:
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
BCL6/1982

Dilution:
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB008813

--


Antigen:
Bcl-6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL6

Immunogen:
Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Tumor Suppressors

Test Specificity:
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
BCL6/1982

Dilution:
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB008815

--


Antigen:
Bcl-6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL6

Immunogen:
Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Tumor Suppressors

Test Specificity:
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
BCL6/1982

Dilution:
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ