NB008891

Tryptase alpha/beta 1 Antibody (TPSAB1/1961), Janelia Fluor™ 549, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB008891-Each-of-1 In Stock ₹ 55,271.76

NB008891 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Tryptase alpha/beta 1

Classification

Monoclonal

Conjugate

Janelia Fluor 549

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Alias

EC:3.4.21.59, epididymis secretory sperm binding protein, mast cell alpha II tryptase, mast cell beta I tryptase, mast cell tryptase, TPS1, TPS2, TPSB1, TPSB2, tryptase alpha II, Tryptase alpha-1, tryptase beta I, tryptase beta-1, Tryptase beta-2, Tryptase I, tryptase II, tryptase-1, tryptase-2, tryptase-I, tryptase-III

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG1 κ

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

TPSAB1/1961

Dilution

Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Accession No.

Q15661

Gene Symbols

TPSAB1

Immunogen

Recombinant human Tryptase alpha/TPS1 protein fragment (around aa 115-233) (Exact sequence is proprietary) (Uniprot: Q15661)

Quantity

0.1 mL

Research Discipline

Immunology, metabolism

Test Specificity

This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis. Due to sequence identity this antibody will likely cross react with tryptase beta 2.

Content And Storage

Store at 4°C in the dark.

Description

  • Tryptase alpha/beta 1 Monoclonal antibody specifically detects Tryptase alpha/beta 1 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

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Img

Novus Biologicals

NB008891

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Antigen:
Tryptase alpha/beta 1

Classification:
Monoclonal

Conjugate:
Janelia Fluor 549

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Alias:
EC:3.4.21.59, epididymis secretory sperm binding protein, mast cell alpha II tryptase, mast cell beta I tryptase, mast cell tryptase, TPS1, TPS2, TPSB1, TPSB2, tryptase alpha II, Tryptase alpha-1, tryptase beta I, tryptase beta-1, Tryptase beta-2, Tryptase I, tryptase II, tryptase-1, tryptase-2, tryptase-I, tryptase-III

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
TPSAB1/1961

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Accession No.:
Q15661

Gene Symbols:
TPSAB1

Immunogen:
Recombinant human Tryptase alpha/TPS1 protein fragment (around aa 115-233) (Exact sequence is proprietary) (Uniprot: Q15661)

Quantity:
0.1 mL

Research Discipline:
Immunology, metabolism

Test Specificity:
This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis. Due to sequence identity this antibody will likely cross react with tryptase beta 2.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NB008893

--


Antigen:
Tryptase alpha/beta 1

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Alias:
EC:3.4.21.59, epididymis secretory sperm binding protein, mast cell alpha II tryptase, mast cell beta I tryptase, mast cell tryptase, TPS1, TPS2, TPSB1, TPSB2, tryptase alpha II, Tryptase alpha-1, tryptase beta I, tryptase beta-1, Tryptase beta-2, Tryptase I, tryptase II, tryptase-1, tryptase-2, tryptase-I, tryptase-III

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
TPSAB1/1961

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Accession No.:
Q15661

Gene Symbols:
TPSAB1

Immunogen:
Recombinant human Tryptase alpha/TPS1 protein fragment (around aa 115-233) (Exact sequence is proprietary) (Uniprot: Q15661)

Quantity:
0.1 mL

Research Discipline:
Immunology, metabolism

Test Specificity:
This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis. Due to sequence identity this antibody will likely cross react with tryptase beta 2.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NB008894

--


Antigen:
Tryptase alpha/beta 1

Classification:
Monoclonal

Conjugate:
DyLight 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Alias:
EC:3.4.21.59, epididymis secretory sperm binding protein, mast cell alpha II tryptase, mast cell beta I tryptase, mast cell tryptase, TPS1, TPS2, TPSB1, TPSB2, tryptase alpha II, Tryptase alpha-1, tryptase beta I, tryptase beta-1, Tryptase beta-2, Tryptase I, tryptase II, tryptase-1, tryptase-2, tryptase-I, tryptase-III

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
TPSAB1/1961

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Accession No.:
Q15661

Gene Symbols:
TPSAB1

Immunogen:
Recombinant human Tryptase alpha/TPS1 protein fragment (around aa 115-233) (Exact sequence is proprietary) (Uniprot: Q15661)

Quantity:
0.1 mL

Research Discipline:
Immunology, metabolism

Test Specificity:
This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis. Due to sequence identity this antibody will likely cross react with tryptase beta 2.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NB008896

--


Antigen:
BOB1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Alias:
B-cell-specific coactivator OBF-1, BOB-1, OBF-1, OBF1BOB1, OCAB, OCA-B, OCT-binding factor 1, POU class 2 associating factor 1, POU domain class 2, associating factor 1, POU domain class 2-associating factor 1, POU domain, class 2, associating factor 1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
BOB1/2425

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Accession No.:
__

Gene Symbols:
POU2AF1

Immunogen:
Recombinant fragment (around aa 148-255) of human BOB1 protein (exact sequence is proprietary) (Uniprot: Q16633)

Quantity:
0.1 mL

Research Discipline:
Immunology

Test Specificity:
BOB1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.

Content And Storage:
Store at 4°C in the dark.