NB008914

BOB1 Antibody (BOB1/2425), DyLight 550, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB008914-Each-of-1 In Stock ₹ 55,271.76

NB008914 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

BOB1

Classification

Monoclonal

Conjugate

DyLight 550

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

POU2AF1

Immunogen

Recombinant fragment (around aa 148-255) of human BOB1 protein (exact sequence is proprietary) (Uniprot: Q16633)

Quantity

0.1 mL

Research Discipline

Immunology

Test Specificity

BOB1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

BOB1/2425

Dilution

Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

B-cell-specific coactivator OBF-1, BOB-1, OBF-1, OBF1BOB1, OCAB, OCA-B, OCT-binding factor 1, POU class 2 associating factor 1, POU domain class 2, associating factor 1, POU domain class 2-associating factor 1, POU domain, class 2, associating factor 1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG2b κ

Description

  • BOB1 Monoclonal specifically detects BOB1 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NB008914

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Antigen:
BOB1

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
POU2AF1

Immunogen:
Recombinant fragment (around aa 148-255) of human BOB1 protein (exact sequence is proprietary) (Uniprot: Q16633)

Quantity:
0.1 mL

Research Discipline:
Immunology

Test Specificity:
BOB1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
BOB1/2425

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B-cell-specific coactivator OBF-1, BOB-1, OBF-1, OBF1BOB1, OCAB, OCA-B, OCT-binding factor 1, POU class 2 associating factor 1, POU domain class 2, associating factor 1, POU domain class 2-associating factor 1, POU domain, class 2, associating factor 1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB008916

--


Antigen:
BOB1

Classification:
Monoclonal

Conjugate:
DyLight 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
POU2AF1

Immunogen:
Recombinant fragment (around aa 148-255) of human BOB1 protein (exact sequence is proprietary) (Uniprot: Q16633)

Quantity:
0.1 mL

Research Discipline:
Immunology

Test Specificity:
BOB1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
BOB1/2425

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B-cell-specific coactivator OBF-1, BOB-1, OBF-1, OBF1BOB1, OCAB, OCA-B, OCT-binding factor 1, POU class 2 associating factor 1, POU domain class 2, associating factor 1, POU domain class 2-associating factor 1, POU domain, class 2, associating factor 1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB008917

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Antigen:
CDX2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CDX2

Immunogen:
Recombinant human full-length CDX2 protein (Uniprot: Q99626)

Quantity:
0.1 mL

Research Discipline:
Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
PCRP-CDX2-1A3

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB008921

--


Antigen:
CDX2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CDX2

Immunogen:
Recombinant human full-length CDX2 protein (Uniprot: Q99626)

Quantity:
0.1 mL

Research Discipline:
Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
PCRP-CDX2-1A3

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ