NB009000

Bcl-2 Antibody (BCL2/2210R), Janelia Fluor™ 549, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB009000-Each-of-1 In Stock ₹ 56,298.48

NB009000 - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

Bcl-2

Classification

Monoclonal

Conjugate

Janelia Fluor 549

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

BCL2

Immunogen

Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Quantity

0.1 mL

Research Discipline

Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors

Test Specificity

This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

BCL2/2210R

Dilution

Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species

Rabbit

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG

Description

  • Bcl-2 Monoclonal specifically detects Bcl-2 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Novus Biologicals

NB009000

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Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
Janelia Fluor 549

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL2

Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
BCL2/2210R

Dilution:
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Rabbit

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG

Img

Novus Biologicals

NB009004

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Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL2

Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
BCL2/2210R

Dilution:
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Rabbit

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG

Img

Novus Biologicals

NB009006

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Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
DyLight 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL2

Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
BCL2/2210R

Dilution:
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Rabbit

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG

Img

Novus Biologicals

NB009008

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Antigen:
PU.1/Spi-1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
SPI1

Immunogen:
Recombinant fragment (around aa 16-170) of human PU.1/Spi-1 protein (Exact sequence is proprietary) (Uniprot: P17947 )

Quantity:
0.1 mL

Research Discipline:
Innate Immunity

Test Specificity:
PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
PU1/2146

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
hematopoietic transcription factor PU.1, OF, PU.1, SFPI131 kDa transforming protein, SPI-1, SPI-1 proto-oncogene, SPI-A, spleen focus forming virus (SFFV) proviral integration oncogene spi1,31 kDa-transforming protein, transcription factor PU.1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ