NB009046

Cytokeratin 10 Antibody (KRT10/1990R), Janelia Fluor™ 646, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB009046-Each-of-1 In Stock ₹ 55,271.76

NB009046 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Cytokeratin 1/10

Classification

Monoclonal

Conjugate

Janelia Fluor 646

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

KRT10

Immunogen

Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)

Quantity

0.1 mL

Research Discipline

Cell Biology, Cellular Markers

Test Specificity

This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

KRT10/1990R

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK

Host Species

Rabbit

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Mouse

Isotype

IgG

Description

  • Cytokeratin 10 Monoclonal specifically detects Cytokeratin 10 in Human, Mouse samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NB009046

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Antigen:
Cytokeratin 1/10

Classification:
Monoclonal

Conjugate:
Janelia Fluor 646

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
KRT10

Immunogen:
Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)

Quantity:
0.1 mL

Research Discipline:
Cell Biology, Cellular Markers

Test Specificity:
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
KRT10/1990R

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK

Host Species:
Rabbit

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Isotype:
IgG

Img

Novus Biologicals

NB009051

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Antigen:
Cytokeratin 1/10

Classification:
Monoclonal

Conjugate:
DyLight 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
KRT10

Immunogen:
Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)

Quantity:
0.1 mL

Research Discipline:
Cell Biology, Cellular Markers

Test Specificity:
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
KRT10/1990R

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK

Host Species:
Rabbit

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Isotype:
IgG

Img

Novus Biologicals

NB009052

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Antigen:
Elastin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
ELN

Immunogen:
Recombinant full-length human Elastin protein (Uniprot: P15502)

Quantity:
0.1 mL

Research Discipline:
Extracellular Matrix

Test Specificity:
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
ELN/1981

Dilution:
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB009054

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Antigen:
Elastin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
ELN

Immunogen:
Recombinant full-length human Elastin protein (Uniprot: P15502)

Quantity:
0.1 mL

Research Discipline:
Extracellular Matrix

Test Specificity:
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
ELN/1981

Dilution:
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ