Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NB009096-Each-of-1 | In Stock | ₹ 55,271.76 |
NB009096 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Filaggrin
Monoclonal
Alexa Fluor 488
50mM Sodium Borate with 0.05% Sodium Azide
FLG
Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
0.1 mL
Cell Biology, Cellular Markers
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Store at 4°C in the dark.
Immunohistochemistry, Immunohistochemistry (Paraffin)
FLG/1563
Immunohistochemistry, Immunohistochemistry-Paraffin
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Mouse
Protein A or G purified
RUO
Primary
Human
IgG2b κ