NPM1, Mouse anti-Human, Clone: NPM1/1902, Novus Biologicals™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB010496-Each-of-1 | In Stock | ₹ 22,930.08 |
NB010496 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,930.08
GST (18%): ₹ 4,127.414
Total Price: ₹ 27,057.494
Antigen
NPM1
Classification
Monoclonal
Concentration
0.2 mg/mL
Dilution
Western Blot 1-2 ug/ml, ELISA 2-4 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Gene Accession No.
P06748, P06748
Gene Symbols
NPM1
Immunogen
Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Quantity
20 μg
Research Discipline
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
Gene ID (Entrez)
4869
Target Species
Human
Form
Purified
Applications
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Clone
NPM1/1902
Conjugate
Unconjugated
Formulation
10 mM PBS with 0.05% BSA
Gene Alias
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This antibody recognizes a 33kDa glycoprotein, identified as Nucleophosmin (NPM1). It is predominantly localized in the nucleus of cells in most tissues. NPM1 is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
Content And Storage
Store at 4°C.
Isotype
IgG2b κ
Related Products
Description
- NPM1 Monoclonal specifically detects NPM1 in Human samples
- It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.
Compare Similar Items
Show Difference
Antigen: NPM1
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Western Blot 1-2 ug/ml, ELISA 2-4 ug/ml, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Gene Accession No.: P06748, P06748
Gene Symbols: NPM1
Immunogen: Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Quantity: 20 μg
Research Discipline: Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
Gene ID (Entrez): 4869
Target Species: Human
Form: Purified
Applications: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Clone: NPM1/1902
Conjugate: Unconjugated
Formulation: 10 mM PBS with 0.05% BSA
Gene Alias: B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody recognizes a 33kDa glycoprotein, identified as Nucleophosmin (NPM1). It is predominantly localized in the nucleus of cells in most tissues. NPM1 is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen: Pax2
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: ELISA, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Gene Accession No.: Q02962, Q02962
Gene Symbols: PAX2
Immunogen: Recombinant fragment (around aa 223-354) human Pax2 protein (exact sequence is proprietary)
Quantity: 100 μg
Research Discipline: Chaperone Mediated Autophagy (CMA), Neuronal Cell Markers, Stem Cell Markers
Gene ID (Entrez): 5076
Target Species: Human
Form: Purified
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Clone: PAX2/1104
Conjugate: Unconjugated
Formulation: 10 mM PBS with 0.05% BSA
Gene Alias: paired box 2, paired box gene 2, paired box homeotic gene 2, paired box protein Pax-2
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody recognizes a protein of 42kDa, which is identified as Pax2. Pax2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen: Pax2
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: ELISA, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Gene Accession No.: Q02962, Q02962
Gene Symbols: PAX2
Immunogen: Recombinant fragment (around aa 223-354) human Pax2 protein (exact sequence is proprietary)
Quantity: 20 μg
Research Discipline: Chaperone Mediated Autophagy (CMA), Neuronal Cell Markers, Stem Cell Markers
Gene ID (Entrez): 5076
Target Species: Human
Form: Purified
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Clone: PAX2/1104
Conjugate: Unconjugated
Formulation: 10 mM PBS with 0.05% BSA
Gene Alias: paired box 2, paired box gene 2, paired box homeotic gene 2, paired box protein Pax-2
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody recognizes a protein of 42kDa, which is identified as Pax2. Pax2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
