NPM1 Antibody (NPM1/3287), DyLight 350, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB011623-Each-of-1 | In Stock | ₹ 55,271.76 |
NB011623 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
NPM1
Classification
Monoclonal
Conjugate
DyLight 350
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
NPM1
Immunogen
Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )
Quantity
0.1 mL
Research Discipline
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
Test Specificity
Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone
NPM1/3287
Dilution
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG2b κ
Related Products
Description
- NPM1 Monoclonal specifically detects NPM1 in Human samples
- It is validated for Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: NPM1
Classification: Monoclonal
Conjugate: DyLight 350
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: NPM1
Immunogen: Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )
Quantity: 0.1 mL
Research Discipline: Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
Test Specificity: Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: NPM1/3287
Dilution: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ
Antigen: NPM1
Classification: Monoclonal
Conjugate: DyLight 405
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: NPM1
Immunogen: Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )
Quantity: 0.1 mL
Research Discipline: Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors
Test Specificity: Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: NPM1/3287
Dilution: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ
Antigen: Pax2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Symbols: PAX2
Immunogen: Recombinant fragment (around aa 223-354) human Pax2 protein (exact sequence is proprietary) (Uniprot: Q02962)
Quantity: 100 μg
Research Discipline: Chaperone Mediated Autophagy (CMA), Neuronal Cell Markers, Stem Cell Markers
Test Specificity: This antibody recognizes a protein of 42kDa, which is identified as Pax2. Pax2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.
Content And Storage: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Clone: PAX2/1104
Dilution: ELISA, Immunohistochemistry 1-2 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array
Gene Alias: paired box 2, paired box gene 2, paired box homeotic gene 2, paired box protein Pax-2
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ
