NB012978

GAD1/GAD67 Antibody (GAD1/2563), DyLight 550, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB012978-Each-of-1 In Stock ₹ 55,271.76

NB012978 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

GAD1/GAD67

Classification

Monoclonal

Conjugate

DyLight 550

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

GAD1

Immunogen

Recombinant human GAD1/GAD67 protein fragment (around aa 72-135) (exact sequence is proprietary) (Uniprot: Q99259)

Quantity

0.1 mL

Research Discipline

Diabetes Research

Test Specificity

This monoclonal antibody recognizes a protein of 67kDa, which is identified as glutamic acid decarboxylase 1 (GDA1). There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD65 (also known as GAD2) and GAD67 (also known as GAD1. GAD65 and GAD67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD65 localizes to synaptic vesicle membranes in nerve terminals, while GAD67 is distributed throughout the cell. GAD67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD65 will transiently activate to assist in GABA production. The loss of GAD65 is detrimental and can impair GABA neurotransmission, however the loss of GAD67 is lethal.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Flow Cytometry, ELISA

Clone

GAD1/2563

Dilution

Western Blot, Flow Cytometry, ELISA

Gene Alias

67kD), EC 4.1.1, FLJ45882, GAD25, glutamate decarboxylase 1 (brain, 67kDa), Glutamate decarboxylase 67 kDa isoform

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG2b κ

Description

  • GAD1/GAD67 Monoclonal specifically detects GAD1/GAD67 in Human samples
  • It is validated for Western Blot, Flow Cytometry, ELISA.

Compare Similar Items

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Img

Novus Biologicals

NB012978

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Antigen:
GAD1/GAD67

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
GAD1

Immunogen:
Recombinant human GAD1/GAD67 protein fragment (around aa 72-135) (exact sequence is proprietary) (Uniprot: Q99259)

Quantity:
0.1 mL

Research Discipline:
Diabetes Research

Test Specificity:
This monoclonal antibody recognizes a protein of 67kDa, which is identified as glutamic acid decarboxylase 1 (GDA1). There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD65 (also known as GAD2) and GAD67 (also known as GAD1. GAD65 and GAD67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD65 localizes to synaptic vesicle membranes in nerve terminals, while GAD67 is distributed throughout the cell. GAD67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD65 will transiently activate to assist in GABA production. The loss of GAD65 is detrimental and can impair GABA neurotransmission, however the loss of GAD67 is lethal.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA

Clone:
GAD1/2563

Dilution:
Western Blot, Flow Cytometry, ELISA

Gene Alias:
67kD), EC 4.1.1, FLJ45882, GAD25, glutamate decarboxylase 1 (brain, 67kDa), Glutamate decarboxylase 67 kDa isoform

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB012980

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Antigen:
GAD1/GAD67

Classification:
Monoclonal

Conjugate:
DyLight 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
GAD1

Immunogen:
Recombinant human GAD1/GAD67 protein fragment (around aa 72-135) (exact sequence is proprietary) (Uniprot: Q99259)

Quantity:
0.1 mL

Research Discipline:
Diabetes Research

Test Specificity:
This monoclonal antibody recognizes a protein of 67kDa, which is identified as glutamic acid decarboxylase 1 (GDA1). There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD65 (also known as GAD2) and GAD67 (also known as GAD1. GAD65 and GAD67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD65 localizes to synaptic vesicle membranes in nerve terminals, while GAD67 is distributed throughout the cell. GAD67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD65 will transiently activate to assist in GABA production. The loss of GAD65 is detrimental and can impair GABA neurotransmission, however the loss of GAD67 is lethal.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA

Clone:
GAD1/2563

Dilution:
Western Blot, Flow Cytometry, ELISA

Gene Alias:
67kD), EC 4.1.1, FLJ45882, GAD25, glutamate decarboxylase 1 (brain, 67kDa), Glutamate decarboxylase 67 kDa isoform

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB012981

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Antigen:
GAD2/GAD65

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Symbols:
GAD2

Immunogen:
Recombinant human GAD2/GAD65 protein fragment (around aa 6-99) (exact sequence is proprietary) (Uniprot: Q05329)

Quantity:
100 μg

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Lipid and Metabolism, Neuronal Cell Markers, Neuroscience

Test Specificity:
This monoclonal antibody recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GAD2/GAD65).

Content And Storage:
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array

Clone:
GAD2/1960

Dilution:
Immunohistochemistry 0.1-0.2 ug/ml, Immunohistochemistry-Paraffin 0.1-0.2 ug/ml, Protein Array

Gene Alias:
EC 4.1.1, EC 4.1.1.15, GAD-65, GAD65MGC161605, glutamate decarboxylase 2, glutamate decarboxylase 2 (pancreatic islets and brain, 65kD), glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), Glutamate decarboxylase 65 kDa isoform, Glutamate decarboxylase-2 (pancreas), MGC161607,65 kDa glutamic acid decarboxylase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB012982

--


Antigen:
GAD2/GAD65

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
GAD2

Immunogen:
Recombinant human GAD2/GAD65 protein fragment (around aa 6-99) (exact sequence is proprietary) (Uniprot: Q05329)

Quantity:
0.1 mL

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Lipid and Metabolism, Neuronal Cell Markers, Neuroscience

Test Specificity:
This monoclonal antibody recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GAD2/GAD65).

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
GAD2/1960

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
EC 4.1.1, EC 4.1.1.15, GAD-65, GAD65MGC161605, glutamate decarboxylase 2, glutamate decarboxylase 2 (pancreatic islets and brain, 65kD), glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), Glutamate decarboxylase 65 kDa isoform, Glutamate decarboxylase-2 (pancreas), MGC161607,65 kDa glutamic acid decarboxylase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ