NB016064

B7-1/CD80, Rabbit anti-Human, Clone: IDEC-114 (Galiximab), Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NB016064-Each-of-1 In Stock ₹ 50,009.82

NB016064 - Each of 1

₹ 50,009.82

In Stock

Quantity

1

Base Price: ₹ 50,009.82

GST (18%): ₹ 9,001.768

Total Price: ₹ 59,011.588

Antigen

B7-1/CD80

Classification

Monoclonal

Concentration

1 mg/mL

Dilution

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional, Block/Neutralize

Gene Alias

Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80

Host Species

Rabbit

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.

Content And Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype

IgG λ

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional Assay, Blocking Assay

Clone

IDEC-114 (Galiximab)

Conjugate

Unconjugated

Formulation

PBS

Gene Symbols

CD80

Immunogen

Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)

Quantity

0.2 mg

Research Discipline

Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Signal Transduction

Gene ID (Entrez)

941

Target Species

Human

Form

Purified

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Description

  • B7-1/CD80 Monoclonal specifically detects B7-1/CD80 in Human samples
  • It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Functional, Block/Neutralize.

Compare Similar Items

Show Difference

Img

Fischer Scientific

NB016064

--


Antigen:
B7-1/CD80

Classification:
Monoclonal

Concentration:
1 mg/mL

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional, Block/Neutralize

Gene Alias:
Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
IgG λ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional Assay, Blocking Assay

Clone:
IDEC-114 (Galiximab)

Conjugate:
Unconjugated

Formulation:
PBS

Gene Symbols:
CD80

Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)

Quantity:
0.2 mg

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Signal Transduction

Gene ID (Entrez):
941

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NB016065

--


Antigen:
B7-1/CD80

Classification:
Monoclonal

Concentration:
__

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Gene Alias:
Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG λ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

Clone:
IDEC-114 (Galiximab)

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate

Gene Symbols:
CD80

Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Signal Transduction

Gene ID (Entrez):
941

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NB016070

--


Antigen:
B7-1/CD80

Classification:
Monoclonal

Concentration:
__

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Gene Alias:
Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG λ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

Clone:
IDEC-114 (Galiximab)

Conjugate:
Alexa Fluor 647

Formulation:
50mM Sodium Borate

Gene Symbols:
CD80

Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Signal Transduction

Gene ID (Entrez):
941

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NB016072

--


Antigen:
B7-1/CD80

Classification:
Monoclonal

Concentration:
__

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Gene Alias:
Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG λ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

Clone:
IDEC-114 (Galiximab)

Conjugate:
Alexa Fluor 750

Formulation:
50mM Sodium Borate

Gene Symbols:
CD80

Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Signal Transduction

Gene ID (Entrez):
941

Target Species:
Human

Form:
Purified