NB016123

Fc gamma RIIIA/CD16a Antibody (3G8), DyLight 594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB016123-Each-of-1 In Stock ₹ 52,277.16

NB016123 - Each of 1

₹ 52,277.16

In Stock

Quantity

1

Base Price: ₹ 52,277.16

GST (18%): ₹ 9,409.889

Total Price: ₹ 61,687.049

Antigen

Fc gamma RIIIA/CD16a

Classification

Monoclonal

Conjugate

DyLight 594

Formulation

50mM Sodium Borate

Gene Symbols

FCGR3A

Immunogen

3G8 was prepared by immunizing mice with human PMN (polymorphonuclear leukocytes) cells.

Quantity

0.1 mL

Research Discipline

Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells

Gene ID (Entrez)

2214

Target Species

Human, Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus Macaque

Form

Purified

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

Clone

3G8

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Gene Alias

CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Host Species

Rabbit

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity).

Content And Storage

Store at 4°C in the dark.

Isotype

IgG κ

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Description

  • Fc gamma RIIIA/CD16a Monoclonal specifically detects Fc gamma RIIIA/CD16a in Human, Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus Macaque samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB016123

--


Antigen:
Fc gamma RIIIA/CD16a

Classification:
Monoclonal

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate

Gene Symbols:
FCGR3A

Immunogen:
3G8 was prepared by immunizing mice with human PMN (polymorphonuclear leukocytes) cells.

Quantity:
0.1 mL

Research Discipline:
Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
2214

Target Species:
Human, Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus Macaque

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

Clone:
3G8

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Gene Alias:
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity).

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG κ

Img

Novus Biologicals

NB016133

--


Antigen:
Fc gamma RIIIA/CD16a

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate

Gene Symbols:
FCGR3A

Immunogen:
3G8 was prepared by immunizing mice with human PMN (polymorphonuclear leukocytes) cells.

Quantity:
0.1 mL

Research Discipline:
Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
2214

Target Species:
Human, Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus Macaque

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

Clone:
3G8

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Gene Alias:
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity).

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG κ

Img

Novus Biologicals

NB016134

--


Antigen:
Fc gamma RIIIA/CD16a

Classification:
Monoclonal

Conjugate:
DyLight 350

Formulation:
50mM Sodium Borate

Gene Symbols:
FCGR3A

Immunogen:
3G8 was prepared by immunizing mice with human PMN (polymorphonuclear leukocytes) cells.

Quantity:
0.1 mL

Research Discipline:
Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
2214

Target Species:
Human, Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus Macaque

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

Clone:
3G8

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Gene Alias:
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity).

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG κ

Img

Fischer Scientific

NB016136

--


Antigen:
EDAR

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS

Gene Symbols:
EDAR

Immunogen:
EDAR12 was prepared by immunixzing female OVE1B mice (with the Edar gene deleted) subcutaneously with mouse EDAR-Fc and positive hybridoma clones were screened for binding mEDAR by ELISA.

Quantity:
0.025 mg

Research Discipline:
Apoptosis

Gene ID (Entrez):
10913

Target Species:
Human, Mouse, Rat, Canine, Chicken

Form:
Purified

Applications:
Western Blot, ELISA, Blocking Assay

Clone:
EDAR12

Dilution:
Western Blot, ELISA, Surface Plasmon Resonance, Block/Neutralize

Gene Alias:
Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, Edar, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
EDAR12 recognises and binds to CRD1 of the extracellular domain of mouse EDAR. EDAR3 cross-reacts with EDAR derived from human, dog, rat and chicken when EDAR is fused to the glycosylphosphatidylinositol anchor of TRAILR3. EDAR is the receptor for the TNF family ligand EDA1, which is a type II transmembrane protein possessing a collagen-like domain and a C-terminal TNF-homology domain. EDAR is important for the correct development of skin appendages including hair, teeth and eccrine sweat glands. LoF mutations in the Eda gene is known to cause XLHED (X-linked hypohidrotic ectodermal dysplasia), and results in abnormal development.

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
IgG κ