NB017553
LAG-3 Antibody (C9B7W) - BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB017553-Each-of-1 | In Stock | ₹ 17,454.24 |
NB017553 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,454.24
GST (18%): ₹ 3,141.763
Total Price: ₹ 20,596.003
Antigen
LAG-3
Classification
Monoclonal
Concentration
1.0 mg/mL
Dilution
Flow Cytometry 1:50 - 1:200
Gene Accession No.
Q61790
Gene Symbols
LAG3
Immunogen
Murine CD223 Ig fusion protein
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG1
Applications
Flow Cytometry
Clone
C9B7W
Conjugate
Unconjugated
Formulation
PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias
CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Host Species
Rat
Molecular Weight of Antigen
57 kDa
Quantity
0.025 mg
Research Discipline
Adaptive Immunity, Immunology, Innate Immunity
Gene ID (Entrez)
3902
Target Species
Mouse
Form
Purified
Related Products
Description
- Description LAG-3 Monoclonal specifically detects LAG-3 in Mouse samples
- It is validated for Flow Cytometry.
Compare Similar Items
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Antigen: LAG-3
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:50 - 1:200
Gene Accession No.: Q61790
Gene Symbols: LAG3
Immunogen: Murine CD223 Ig fusion protein
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Flow Cytometry
Clone: C9B7W
Conjugate: Unconjugated
Formulation: PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias: CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Host Species: Rat
Molecular Weight of Antigen: 57 kDa
Quantity: 0.025 mg
Research Discipline: Adaptive Immunity, Immunology, Innate Immunity
Gene ID (Entrez): 3902
Target Species: Mouse
Form: Purified
Antigen:
LAG-3
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:50 - 1:200
Gene Accession No.:
Q61790
Gene Symbols:
LAG3
Immunogen:
Murine CD223 Ig fusion protein
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
C9B7W
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias:
CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Host Species:
Rat
Molecular Weight of Antigen:
57 kDa
Quantity:
0.025 mg
Research Discipline:
Adaptive Immunity, Immunology, Innate Immunity
Gene ID (Entrez):
3902
Target Species:
Mouse
Form:
Purified
Antigen: CD8
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500
Gene Accession No.: __
Gene Symbols: CD8A
Immunogen: Made to Rabbit CD8
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes the rabbit CD8 cell surface antigen, expressed by a subset of T lymphocytes with cytotoxic/suppressor activity.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunohistochemistry, Immunocytochemistry
Clone: 12.C7
Conjugate: Unconjugated
Formulation: Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias: CD8, CD8a molecule, LEU2, p32
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.025 mg
Research Discipline: Innate Immunity, Stem Cell Markers
Gene ID (Entrez): 925
Target Species: Rabbit
Form: Purified
Antigen:
CD8
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500
Gene Accession No.:
__
Gene Symbols:
CD8A
Immunogen:
Made to Rabbit CD8
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes the rabbit CD8 cell surface antigen, expressed by a subset of T lymphocytes with cytotoxic/suppressor activity.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunohistochemistry, Immunocytochemistry
Clone:
12.C7
Conjugate:
Unconjugated
Formulation:
Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias:
CD8, CD8a molecule, LEU2, p32
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.025 mg
Research Discipline:
Innate Immunity, Stem Cell Markers
Gene ID (Entrez):
925
Target Species:
Rabbit
Form:
Purified
Antigen: CD94
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:50-1:100
Gene Accession No.: Q13241
Gene Symbols: KLRD1
Immunogen: Natural killer cell line
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-64104 is specific for human CD94, also known as KLRD1 (Killer cell lectin-like receptor, subfamily D, member 1). CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes. CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes. Clone DX22 is reported to inhibit the binding of CD94 to HLA-E(2) and HLA-G(4).
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Flow Cytometry
Clone: DX22
Conjugate: Unconjugated
Formulation: PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias: CD94 antigen, CD94natural killer cells antigen CD94, Killer cell lectin-like receptor subfamily D member 1, killer cell lectin-like receptor subfamily D, member 1, KP43, NK cell receptor
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.025 mg
Research Discipline: Innate Immunity
Gene ID (Entrez): 3824
Target Species: Human
Form: Purified
Antigen:
CD94
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:50-1:100
Gene Accession No.:
Q13241
Gene Symbols:
KLRD1
Immunogen:
Natural killer cell line
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-64104 is specific for human CD94, also known as KLRD1 (Killer cell lectin-like receptor, subfamily D, member 1). CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes. CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes. Clone DX22 is reported to inhibit the binding of CD94 to HLA-E(2) and HLA-G(4).
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
DX22
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias:
CD94 antigen, CD94natural killer cells antigen CD94, Killer cell lectin-like receptor subfamily D member 1, killer cell lectin-like receptor subfamily D, member 1, KP43, NK cell receptor
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.025 mg
Research Discipline:
Innate Immunity
Gene ID (Entrez):
3824
Target Species:
Human
Form:
Purified
Antigen: HLA DQ/DR/DP
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:100-1:200
Gene Accession No.: P01909
Gene Symbols: HLA-DQA1
Immunogen: Made to Human HLA DP DQ DR
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-64162 recognizes the beta chains of class II human major histocompatibility (MHC) antigens. The antibody reacts with DP, DQ, DR beta chains, which are expressed by antigen presenting cells, B- cells, monocytes and activated T lymphocytes.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Flow Cytometry
Clone: Bu26
Conjugate: Unconjugated
Formulation: PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias: CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.025 mg
Research Discipline: Adaptive Immunity, Asthma, Immunology
Gene ID (Entrez): 3117
Target Species: Human
Form: Purified
Antigen:
HLA DQ/DR/DP
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:100-1:200
Gene Accession No.:
P01909
Gene Symbols:
HLA-DQA1
Immunogen:
Made to Human HLA DP DQ DR
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-64162 recognizes the beta chains of class II human major histocompatibility (MHC) antigens. The antibody reacts with DP, DQ, DR beta chains, which are expressed by antigen presenting cells, B- cells, monocytes and activated T lymphocytes.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
Bu26
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias:
CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.025 mg
Research Discipline:
Adaptive Immunity, Asthma, Immunology
Gene ID (Entrez):
3117
Target Species:
Human
Form:
Purified