NB017747

Feline Leukaemia Virus p15E Antibody (PF6J-2A1) - BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 NB017747-Each-of-1 In Stock ₹ 17,454.24

NB017747 - Each of 1

₹ 17,454.24

In Stock

Quantity

1

Base Price: ₹ 17,454.24

GST (18%): ₹ 3,141.763

Total Price: ₹ 20,596.003

Antigen

Feline Leukaemia Virus p15E

Classification

Monoclonal

Concentration

1 mg/mL

Dilution

Western Blot 1:2000, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500

Gene Accession No.

Q85525

Host Species

Mouse

Purification Method

Protein A purified

Regulatory Status

RUO

Test Specificity

NB100-65808 recognizes an epitope within the amino-terminal domain of both the 20kDa full-length (including intracellular sequence), and the 15kDa truncated forms, of feline leukaemia virus (FeLV) p15e transmembrane envelope protein. Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). Studies have shown strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG2a

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

PF6J-2A1

Conjugate

Unconjugated

Formulation

Phosphate buffered saline with 0.05% Sodium Azide

Gene Alias

Env polyprotein, Feline Leukemia Virus glycoprotein 70, Glycoprotein gp70 [Precursor], GP70 envelope protein, gp70 protein (SU), p15E protein, p15E protein (TM)

Immunogen

Made to Viral FELINE LEUKAEMIA VIRUS p15E

Quantity

0.025 mg

Primary or Secondary

Primary

Target Species

Virus

Form

Purified

Description

  • Feline Leukaemia Virus p15E Monoclonal specifically detects Feline Leukaemia Virus p15E in Virus samples
  • It is validated for Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin.

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Fischer Scientific

NB017747

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Antigen:
Feline Leukaemia Virus p15E

Classification:
Monoclonal

Concentration:
1 mg/mL

Dilution:
Western Blot 1:2000, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500

Gene Accession No.:
Q85525

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
RUO

Test Specificity:
NB100-65808 recognizes an epitope within the amino-terminal domain of both the 20kDa full-length (including intracellular sequence), and the 15kDa truncated forms, of feline leukaemia virus (FeLV) p15e transmembrane envelope protein. Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). Studies have shown strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
PF6J-2A1

Conjugate:
Unconjugated

Formulation:
Phosphate buffered saline with 0.05% Sodium Azide

Gene Alias:
Env polyprotein, Feline Leukemia Virus glycoprotein 70, Glycoprotein gp70 [Precursor], GP70 envelope protein, gp70 protein (SU), p15E protein, p15E protein (TM)

Immunogen:
Made to Viral FELINE LEUKAEMIA VIRUS p15E

Quantity:
0.025 mg

Primary or Secondary:
Primary

Target Species:
Virus

Form:
Purified

Img

Fischer Scientific

NB017749

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Antigen:
ART2.2/Art2b

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:10-1:1000, Immunoprecipitation 1:10-1:500

Gene Accession No.:
O35975

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
RUO

Test Specificity:
NB100-65853 recognizes the gene product of the mouse ADP-ribosyltransferase (ART) 2.2 gene, an ortholog of rat RT6. ART2.2 expressed exclusively by mature T-cells. Levels of ART2.2 expression vary between inbred strains of mice and is absent in NZW mice, in which the ART2.2 gene is deleted (PMID: 10570289, Koch-Nolte et al. 1999).

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
Nika102

Conjugate:
Unconjugated

Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide

Gene Alias:
ADP-ribosyltransferase 2b, Rt6, Rt-6, Rt6.2, Rt6-2

Immunogen:
pME.CD8LF-ART2.2

Quantity:
0.025 mg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Img

Fischer Scientific

NB017750

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Antigen:
KIR2DL3/CD158b2

Classification:
Monoclonal

Concentration:
1 mg/mL

Dilution:
Flow Cytometry 1:10-1:50, Immunoprecipitation 1:10-1:500

Gene Accession No.:
P43628

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Test Specificity:
NB100-65875 recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
GL183

Conjugate:
Unconjugated

Formulation:
PBS, 0.5% Bovine Serum Albumin with 0.09% Sodium Azide

Gene Alias:
CD158 antigen-like family member B2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, NKAT2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor

Immunogen:
NK cell clone E57

Quantity:
0.025 mg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NB017752

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Antigen:
2B4/CD244/SLAMF4

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:50-1:200, Immunoprecipitation 1:10-1:500

Gene Accession No.:
Q9BZW8

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Test Specificity:
NB100-65889 is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
2B4.69

Conjugate:
Unconjugated

Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide

Gene Alias:
CD244 antigen, CD244 molecule, natural killer cell receptor 2B4, h2B4, NAILNK cell activation-inducing ligand, natural killer cell receptor 2B4, NKR2B4NK cell type I receptor protein 2B4,2B4CD244 natural killer cell receptor 2B4, Nmrk, SLAMF4NK cell activation inducing ligand NAIL

Immunogen:
CD244 Fusion protein.

Quantity:
0.025 mg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified