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NB017762

NKG2D/CD314 Antibody (1D11) - Low Endotoxin, Azide and BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 NB017762-Each-of-1 In Stock ₹ 17,668.14

NB017762 - Each of 1

₹ 17,668.14

In Stock

Quantity

1

Base Price: ₹ 17,668.14

GST (18%): ₹ 3,180.265

Total Price: ₹ 20,848.405

Antigen

NKG2D/CD314

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready, Functional Assay

Gene Accession No.

P26718

Gene Symbols

KLRK1

Immunogen

NKL cells.

Quantity

0.05 mg

Primary or Secondary

Primary

Test Specificity

NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).

Content And Storage

Store at -20C. Avoid freeze-thaw cycles.

Isotype

IgG1

Applications

Immunohistochemistry (Frozen), Functional Assay, CyTOF, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

1D11

Conjugate

Unconjugated

Formulation

Phosphate buffered saline with No Preservative

Gene Alias

CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence

Host Species

Mouse

Purification Method

Protein A purified

Regulatory Status

RUO

Gene ID (Entrez)

22914

Target Species

Human

Form

Purified

Description

  • NKG2D/CD314 Monoclonal specifically detects NKG2D/CD314 in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready, Functional Assay.

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Fischer Scientific

NB017762

--

Antigen:
NKG2D/CD314
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready, Functional Assay
Gene Accession No.:
P26718
Gene Symbols:
KLRK1
Immunogen:
NKL cells.
Quantity:
0.05 mg
Primary or Secondary:
Primary
Test Specificity:
NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Content And Storage:
Store at -20C. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Immunohistochemistry (Frozen), Functional Assay, CyTOF, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
1D11
Conjugate:
Unconjugated
Formulation:
Phosphate buffered saline with No Preservative
Gene Alias:
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
22914
Target Species:
Human
Form:
Purified

Img

Fischer Scientific

NB017763

--

Antigen:
Methotrexate
Classification:
Polyclonal
Concentration:
__
Dilution:
ELISA 1:100-1:2000
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Methotrexate (4-amino-10-methylpteroyl-L-glutamic acid) conjugated via the carboxyl groups of the glutamic acid residue to KLH.
Quantity:
0.05 mL
Primary or Secondary:
Primary
Test Specificity:
NB100-65997 is specific for Methotrexate and exhibits the following cross reactivities with related compounds: Aminopterin (18%), Folic acid (<0.01%), Dyhydrofolic acid (<0.01%), Tetrahydrofolic acid (<0.01%), N-5-Methyltetrahydrofolic acid (<0.01%), Folinic acid (<0.01%), N-(p-Aminobenzoyl)-L-glutamic acid (<0.01%).
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG
Applications:
ELISA
Clone:
__
Conjugate:
Unconjugated
Formulation:
Whole antisera with 0.09% Sodium Azide
Gene Alias:
MTX
Host Species:
Sheep
Purification Method:
Unpurified
Regulatory Status:
RUO
Gene ID (Entrez):
__
Target Species:
Non-species specific
Form:
Antisera

Img

Fischer Scientific

NB017768

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Antigen:
Borrelia Burgdorferi
Classification:
Monoclonal
Concentration:
1 mg/mL
Dilution:
Western Blot 1:100-1:2000, ELISA 1:100-1:2000
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Native
Quantity:
0.025 mg
Primary or Secondary:
Primary
Test Specificity:
NB100-66394 recognizes Borrelia burgdorferi, a gram-negative spirochete that is a causative agent of lyme disease in humans.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2a
Applications:
ELISA, Western Blot
Clone:
BGN/F44/42
Conjugate:
Unconjugated
Formulation:
PBS with 0.09% Sodium Azide
Gene Alias:
B burgdorferi, B. burgdorferi, B.burgdorferi, Lyme disease
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
__
Target Species:
Bacteria
Form:
Purified

Img

Fischer Scientific

NB017772

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Antigen:
GO Protein alpha
Classification:
Polyclonal
Concentration:
5.0 mg/mL
Dilution:
Western Blot 1:100-1:2000, ELISA 1:500-1:1000
Gene Accession No.:
P18872
Gene Symbols:
GNAO1
Immunogen:
Synthetic peptide corresponding to the amino acids 345 - 354 of the native molecule conjugated to Keyhole Limpet Haemocyanin.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
G PROTEIN ALPHA 0
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG
Applications:
ELISA, Western Blot
Clone:
__
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.2) with 0.09% Sodium Azide
Gene Alias:
DKFZp686O0962, G-ALPHA-o, GNAO, guanine nucleotide binding protein (G protein), alpha activating activitypolypeptide O, guanine nucleotide binding protein, alpha activating polypeptide O, guanine nucleotide-binding protein G(o) subunit alpha
Host Species:
Rabbit
Purification Method:
Protein G purified
Regulatory Status:
RUO
Gene ID (Entrez):
2775
Target Species:
Drosophila, Mouse
Form:
Purified