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NB018087

Integrin alpha 4/CD49d Antibody (HP2/1) - BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 NB018087-Each-of-1 In Stock ₹ 17,668.14

NB018087 - Each of 1

₹ 17,668.14

In Stock

Quantity

1

Base Price: ₹ 17,668.14

GST (18%): ₹ 3,180.265

Total Price: ₹ 20,848.405

Antigen

Integrin alpha 4/CD49d

Classification

Monoclonal

Concentration

1 mg/mL

Dilution

Flow Cytometry 1ug/5 x 10^5 cells, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Accession No.

P13612

Gene Symbols

ITGA4

Immunogen

JM leukaemia line (Human).

Quantity

0.025 mg

Research Discipline

Cancer, Cellular Markers, Cytoskeleton Markers

Gene ID (Entrez)

3676

Target Species

Human

Form

Purified

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

HP2/1

Conjugate

Unconjugated

Formulation

PBS with 0.09% Sodium Azide

Gene Alias

269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 1995). Mouse anti Human CD49d, clone HP2/1 can be used in basic studies of VLA-4 mediated adhesion and its interaction with the VCAM-1 structure and has been demonstrated to inhibit cell binding to soluble VCAM-1 (Weller et al. 1991).

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG1

Description

  • Description Integrin alpha 4/CD49d Monoclonal specifically detects Integrin alpha 4/CD49d in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Frozen.

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Fischer Scientific

NB018087

--

Antigen:
Integrin alpha 4/CD49d
Classification:
Monoclonal
Concentration:
1 mg/mL
Dilution:
Flow Cytometry 1ug/5 x 10^5 cells, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.:
P13612
Gene Symbols:
ITGA4
Immunogen:
JM leukaemia line (Human).
Quantity:
0.025 mg
Research Discipline:
Cancer, Cellular Markers, Cytoskeleton Markers
Gene ID (Entrez):
3676
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
HP2/1
Conjugate:
Unconjugated
Formulation:
PBS with 0.09% Sodium Azide
Gene Alias:
269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 1995). Mouse anti Human CD49d, clone HP2/1 can be used in basic studies of VLA-4 mediated adhesion and its interaction with the VCAM-1 structure and has been demonstrated to inhibit cell binding to soluble VCAM-1 (Weller et al. 1991).
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1

Img

Fischer Scientific

NB018088

--

Antigen:
RGS3
Classification:
Polyclonal
Concentration:
0.2 mg/mL
Dilution:
Western Blot, Immunoprecipitation
Gene Accession No.:
P49796
Gene Symbols:
RGS3
Immunogen:
E. coli expressed human RGS 3 (amino acids 401-519).
Quantity:
0.025 mg
Research Discipline:
Signal Transduction
Gene ID (Entrez):
5998
Target Species:
Human
Form:
__
Applications:
Western Blot, Immunoprecipitation
Clone:
__
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.2), 1% BSA, 50% Glycerol with 0.02% Sodium Azide
Gene Alias:
C2PA, FLJ20370, FLJ31516, FLJ90496, PDZ-RGS3, regulator of G-protein signaling 3, regulator of G-protein signalling 3, RGP3
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Isotype:
IgG

Img

Fischer Scientific

NB018090

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Antigen:
CD45RC
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:100-1:1000, Immunohistochemistry-Frozen 1:100-1:1000
Gene Accession No.:
__
Gene Symbols:
PTPRC
Immunogen:
Rat lymphocytes stimulated in culture with phytohaemagglutinin.
Quantity:
0.025 mg
Research Discipline:
Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Microglia Markers, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
5788
Target Species:
Rat
Form:
Purified
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry, Immunohistochemistry (Paraffin), Flow Cytometry
Clone:
OX22
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB120-6406 recognizes rat CD45RC, the high molecular weight form of the leucocyte common antigen. This antigen is found on B cells, approximately 50% of bone marrow cells, all CD8+ve T cells, but splits CD4+ve T cells into two populations,CD4+ CD45RC (Th 1-like) and CD4+ CD45RC low (Th-2 like). This product is routinely tested in flow cytometry on rat splenocytes.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1

Img

Fischer Scientific

NB018091

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Antigen:
Helicobacter Pylori
Classification:
Polyclonal
Concentration:
__
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Total lysate of H. pylori.
Quantity:
0.1 mL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Bacteria
Form:
Purified
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Conjugate:
Unconjugated
Formulation:
EDTA, pH 8.0, containing less than 0.1% sodium azide with Sodium Azide
Gene Alias:
H. pylori
Host Species:
Rabbit
Purification Method:
Affinity purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This reacts with heat stable, somatic antigens of the whole H. pylori organism.
Content And Storage:
Store at 4°C.
Isotype:
IgG