SerpinB9 Antibody (7D8), Janelia Fluor™ 549, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB064359549-Each-of-1 | In Stock | ₹ 53,218.32 |
NB064359549 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,218.32
GST (18%): ₹ 9,579.298
Total Price: ₹ 62,797.618
Antigen
SerpinB9
Classification
Monoclonal
Conjugate
Janelia Fluor 549
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
SERPINB9
Immunogen
Recombinant PI-9 produced in P. pastoris.
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD
Content And Storage
Store at 4°C in the dark.
Isotype
IgG1
Applications
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
7D8
Dilution
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species
Mouse
Purification Method
Protein G purified
Research Discipline
Apoptosis, Immunology
Gene ID (Entrez)
5272
Target Species
Human, Mouse, Porcine
Form
Purified
Related Products
Description
- SerpinB9 Monoclonal specifically detects SerpinB9 in Human, Mouse (Negative), Porcine (Negative) samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Compare Similar Items
Show Difference
Antigen: SerpinB9
Classification: Monoclonal
Conjugate: Janelia Fluor 549
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: SERPINB9
Immunogen: Recombinant PI-9 produced in P. pastoris.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD
Content And Storage: Store at 4°C in the dark.
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 7D8
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species: Mouse
Purification Method: Protein G purified
Research Discipline: Apoptosis, Immunology
Gene ID (Entrez): 5272
Target Species: Human, Mouse, Porcine
Form: Purified
Antigen: SerpinB9
Classification: Monoclonal
Conjugate: Janelia Fluor 646
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: SERPINB9
Immunogen: Recombinant PI-9 produced in P. pastoris.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD
Content And Storage: Store at 4°C in the dark.
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: 7D8
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species: Mouse
Purification Method: Protein G purified
Research Discipline: Apoptosis, Immunology
Gene ID (Entrez): 5272
Target Species: Human, Mouse, Porcine
Form: Purified
Antigen: CD19
Classification: Monoclonal
Conjugate: Janelia Fluor 549
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CD19
Immunogen: Human EB-4 Burkitt lymphoma cell line.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: NB100-64360 recognizes human CD19, a 95kD cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
Content And Storage: Store at 4°C in the dark.
Isotype: IgG1
Applications: Flow Cytometry
Clone: Bu12
Dilution: Flow Cytometry
Gene Alias: B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species: Mouse
Purification Method: Protein G purified
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Gene ID (Entrez): 930
Target Species: Human
Form: Purified