NB10056598W

RB1 Antibody (172C1094), Alexa Fluor™ 405 - (cleaved), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB10056598W-Each-of-1 In Stock ₹ 52,961.64

NB10056598W - Each of 1

₹ 52,961.64

In Stock

Quantity

1

Base Price: ₹ 52,961.64

GST (18%): ₹ 9,533.095

Total Price: ₹ 62,494.735

Antigen

cleaved Retinoblastoma 1

Classification

Monoclonal

Conjugate

Alexa Fluor 405

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

RB1

Immunogen

A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.

Quantity

0.1 mL

Research Discipline

Cancer, Cell Cycle and Replication, Transcription Factors and Regulators, Tumor Suppressors

Gene ID (Entrez)

5925

Target Species

Human, Mouse

Form

Purified

Applications

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown

Clone

172C1094

Dilution

Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated

Gene Alias

OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).

Content And Storage

Store at 4C in the dark.

Isotype

IgG1

Related Products

Img

Novus Biologicals

NB10056598Y

--

Img

Novus Biologicals

NB005716

--

Img

Novus Biologicals

NB007198

--

Img

Novus Biologicals

NB007197

--

Img

Novus Biologicals

NB012021

--

Img

Novus Biologicals

NB006145

--

Img

Novus Biologicals

NB006148

--

Img

Novus Biologicals

NB006383

--

Description

  • RB1 Monoclonal specifically detects RB1 in Human, Mouse samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB10056598W

--


Antigen:
cleaved Retinoblastoma 1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
RB1

Immunogen:
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Transcription Factors and Regulators, Tumor Suppressors

Gene ID (Entrez):
5925

Target Species:
Human, Mouse

Form:
Purified

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown

Clone:
172C1094

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated

Gene Alias:
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Img

Novus Biologicals

NB10056598Y

--


Antigen:
cleaved Retinoblastoma 1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
RB1

Immunogen:
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Transcription Factors and Regulators, Tumor Suppressors

Gene ID (Entrez):
5925

Target Species:
Human, Mouse

Form:
Purified

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown

Clone:
172C1094

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated

Gene Alias:
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Img

Novus Biologicals

NB10056598Z

--


Antigen:
cleaved Retinoblastoma 1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
RB1

Immunogen:
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Transcription Factors and Regulators, Tumor Suppressors

Gene ID (Entrez):
5925

Target Species:
Human, Mouse

Form:
Purified

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown

Clone:
172C1094

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated

Gene Alias:
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Img

Novus Biologicals

NB100566

--


Antigen:
TAF15

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
Tris-Citrate/Phosphate (pH 7.0 - 8.0) with 0.09% Sodium Azide

Gene Symbols:
TAF15

Immunogen:
A synthetic peptide which maps to a region between residues 175 and 225 of human TAFII68 using the numbering given in Swiss-Prot entry Q92804 (GeneID 8148).

Quantity:
100 μL

Research Discipline:
DNA Repair

Gene ID (Entrez):
8148

Target Species:
Human

Form:
__

Applications:
Western Blot, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
__

Dilution:
Western Blot 1:5000-1:20000, Immunohistochemistry 1:1000 - 1:5000, Immunoprecipitation 1-4 ug/mg lysate, Immunohistochemistry-Paraffin 1:1000 - 1:5000

Gene Alias:
68kDa, hTAFII68, Npl3, RBP56TAFII68, RNA-binding protein 56, TAF(II)68, TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, TAF2NRBP56/CSMF fusion, TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD(RNA-binding protein 56), TATA box-binding protein-associated factor 2N (RNA-binding protein 56), TATA-binding protein-associated factor 2N, TBP-associated factor 15,68 kDa TATA-binding protein-associated factor

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-566 is specific for human TAFII-68 protein.

Content And Storage:
Store at 4C. Do not freeze.

Isotype:
IgG