Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NB10056598W-Each-of-1 | In Stock | ₹ 52,961.64 |
NB10056598W - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,961.64
GST (18%): ₹ 9,533.095
Total Price: ₹ 62,494.735
cleaved Retinoblastoma 1
Monoclonal
Alexa Fluor 405
50mM Sodium Borate with 0.05% Sodium Azide
RB1
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.
0.1 mL
Cancer, Cell Cycle and Replication, Transcription Factors and Regulators, Tumor Suppressors
5925
Human, Mouse
Purified
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown
172C1094
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
Mouse
Protein G purified
RUO
Primary
The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).
Store at 4C in the dark.
IgG1