NB10063601F
LAG-3 Antibody (C9B7W), FITC, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB10063601F-Each-of-1 | In Stock | ₹ 52,191.60 |
NB10063601F - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,191.60
GST (18%): ₹ 9,394.488
Total Price: ₹ 61,586.088
Antigen
LAG-3
Classification
Monoclonal
Conjugate
FITC
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
LAG3
Immunogen
Murine CD223 Ig fusion protein
Quantity
0.125 mL
Research Discipline
Adaptive Immunity, Immunology, Innate Immunity
Gene ID (Entrez)
3902
Target Species
Mouse
Form
Purified
Applications
Flow Cytometry
Clone
C9B7W
Dilution
Flow Cytometry
Gene Alias
CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Host Species
Rat
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Content And Storage
Store at 4C in the dark.
Isotype
IgG1
Related Products
Description
- Description LAG-3 Monoclonal specifically detects LAG-3 in Mouse samples
- It is validated for Flow Cytometry.
Compare Similar Items
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Antigen: LAG-3
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: LAG3
Immunogen: Murine CD223 Ig fusion protein
Quantity: 0.125 mL
Research Discipline: Adaptive Immunity, Immunology, Innate Immunity
Gene ID (Entrez): 3902
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry
Clone: C9B7W
Dilution: Flow Cytometry
Gene Alias: CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Content And Storage: Store at 4C in the dark.
Isotype: IgG1
Antigen:
LAG-3
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
LAG3
Immunogen:
Murine CD223 Ig fusion protein
Quantity:
0.125 mL
Research Discipline:
Adaptive Immunity, Immunology, Innate Immunity
Gene ID (Entrez):
3902
Target Species:
Mouse
Form:
Purified
Applications:
Flow Cytometry
Clone:
C9B7W
Dilution:
Flow Cytometry
Gene Alias:
CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1
Antigen: DPPIV/CD26
Classification: Monoclonal
Conjugate: Biotin
Formulation: __
Gene Symbols: DPP4
Immunogen: Made to Mouse CD26
Quantity: 0.1 mg
Research Discipline: Adaptive Immunity, GPCR, Immunology
Gene ID (Entrez): 1803
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry
Clone: H207-1082
Dilution: Flow Cytometry 1:10-1:1000
Gene Alias: ADABP, ADCP-2, ADCP2DPP IV, Adenosine deaminase complexing protein 2TP103, CD26 antigen, CD26T-cell activation antigen CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidyl-peptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPPIV, EC 3.4.14.5
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-62997 recognises mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma. The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2a
Antigen:
DPPIV/CD26
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
__
Gene Symbols:
DPP4
Immunogen:
Made to Mouse CD26
Quantity:
0.1 mg
Research Discipline:
Adaptive Immunity, GPCR, Immunology
Gene ID (Entrez):
1803
Target Species:
Mouse
Form:
Purified
Applications:
Flow Cytometry
Clone:
H207-1082
Dilution:
Flow Cytometry 1:10-1:1000
Gene Alias:
ADABP, ADCP-2, ADCP2DPP IV, Adenosine deaminase complexing protein 2TP103, CD26 antigen, CD26T-cell activation antigen CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidyl-peptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPPIV, EC 3.4.14.5
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-62997 recognises mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma. The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2a
Antigen: DPPIV/CD26
Classification: Monoclonal
Conjugate: FITC
Formulation: __
Gene Symbols: DPP4
Immunogen: Made to Mouse CD26
Quantity: 0.1 mg
Research Discipline: Adaptive Immunity, GPCR, Immunology
Gene ID (Entrez): 1803
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry
Clone: H207-1082
Dilution: Flow Cytometry 1:10-1:1000
Gene Alias: ADABP, ADCP-2, ADCP2DPP IV, Adenosine deaminase complexing protein 2TP103, CD26 antigen, CD26T-cell activation antigen CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidyl-peptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPPIV, EC 3.4.14.5
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-62997 recognises mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma. The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2a
Antigen:
DPPIV/CD26
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
__
Gene Symbols:
DPP4
Immunogen:
Made to Mouse CD26
Quantity:
0.1 mg
Research Discipline:
Adaptive Immunity, GPCR, Immunology
Gene ID (Entrez):
1803
Target Species:
Mouse
Form:
Purified
Applications:
Flow Cytometry
Clone:
H207-1082
Dilution:
Flow Cytometry 1:10-1:1000
Gene Alias:
ADABP, ADCP-2, ADCP2DPP IV, Adenosine deaminase complexing protein 2TP103, CD26 antigen, CD26T-cell activation antigen CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidyl-peptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPPIV, EC 3.4.14.5
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-62997 recognises mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma. The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2a
Antigen: CD4
Classification: Monoclonal
Conjugate: DyLight 650
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CD4
Immunogen: Made to Rat CD4 Antibody
Quantity: 0.125 mL
Research Discipline: Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Immunology, Innate Immunity, Regulatory Immunology, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 920
Target Species: Rat
Form: Purified
Applications: Flow Cytometry
Clone: OX-68
Dilution: Flow Cytometry
Gene Alias: CD4 antigen, CD4 antigen (p55), CD4 molecule, CD4 receptor, CD4mut, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes domains 3 and 4 of rat CD4
Content And Storage: Store at 4C in the dark.
Isotype: IgG2a
Antigen:
CD4
Classification:
Monoclonal
Conjugate:
DyLight 650
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
CD4
Immunogen:
Made to Rat CD4 Antibody
Quantity:
0.125 mL
Research Discipline:
Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Immunology, Innate Immunity, Regulatory Immunology, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
920
Target Species:
Rat
Form:
Purified
Applications:
Flow Cytometry
Clone:
OX-68
Dilution:
Flow Cytometry
Gene Alias:
CD4 antigen, CD4 antigen (p55), CD4 molecule, CD4 receptor, CD4mut, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes domains 3 and 4 of rat CD4
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2a