NB10064359G

SerpinB9 Antibody (7D8), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB10064359G-Each-of-1 In Stock ₹ 53,218.32

NB10064359G - Each of 1

₹ 53,218.32

In Stock

Quantity

1

Base Price: ₹ 53,218.32

GST (18%): ₹ 9,579.298

Total Price: ₹ 62,797.618

Antigen

SerpinB9

Classification

Monoclonal

Conjugate

DyLight 488

Gene Accession No.

P50453

Gene Symbols

SERPINB9

Immunogen

Recombinant PI-9 produced in P. pastoris.

Quantity

0.1 mL

Research Discipline

Apoptosis, Immunology

Gene ID (Entrez)

5272

Target Species

Human, Mouse (Negative), Porcine (Negative)

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

7D8

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias

CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage

Store at 4C in the dark.

Isotype

IgG1

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Description

  • SerpinB9 Monoclonal specifically detects SerpinB9 in Human, Mouse (Negative), Porcine (Negative) samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB10064359G

--


Antigen:
SerpinB9

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Accession No.:
P50453

Gene Symbols:
SERPINB9

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Immunology

Gene ID (Entrez):
5272

Target Species:
Human, Mouse (Negative), Porcine (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
7D8

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Img

Novus Biologicals

NB10064359I

--


Antigen:
SerpinB9

Classification:
Monoclonal

Conjugate:
DyLight 755

Gene Accession No.:
P50453

Gene Symbols:
SERPINB9

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Immunology

Gene ID (Entrez):
5272

Target Species:
Human, Mouse (Negative), Porcine (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
7D8

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Img

Novus Biologicals

NB10064359J

--


Antigen:
SerpinB9

Classification:
Monoclonal

Conjugate:
APC

Gene Accession No.:
P50453

Gene Symbols:
SERPINB9

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Immunology

Gene ID (Entrez):
5272

Target Species:
Human, Mouse (Negative), Porcine (Negative)

Form:
Purified

Applications:
Flow Cytometry

Clone:
7D8

Dilution:
Flow Cytometry

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Img

Novus Biologicals

NB10064359Q

--


Antigen:
SerpinB9

Classification:
Monoclonal

Conjugate:
PE

Gene Accession No.:
P50453

Gene Symbols:
SERPINB9

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Immunology

Gene ID (Entrez):
5272

Target Species:
Human, Mouse (Negative), Porcine (Negative)

Form:
Purified

Applications:
Flow Cytometry

Clone:
7D8

Dilution:
Flow Cytometry

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1