NB10064375X

OX40/TNFRSF4 Antibody (7D6), Alexa Fluor™ 488

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB10064375X-Each-of-1 In Stock ₹ 50,052.60

NB10064375X - Each of 1

₹ 50,052.60

In Stock

Quantity

1

Base Price: ₹ 50,052.60

GST (18%): ₹ 9,009.468

Total Price: ₹ 59,062.068

Antigen

OX40/TNFRSF4

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

TNFRSF4

Immunogen

CHO-derived feline CD134-Fc fusion protein.

Quantity

0.1 mL

Research Discipline

Cancer, Cell Cycle and Replication, Immunology

Gene ID (Entrez)

7293

Reconstitution

Protein A purified

Content And Storage

Store at 4C in the dark.

Isotype

IgG1

Applications

Western Blot, Flow Cytometry

Clone

7D6

Dilution

Western Blot, Flow Cytometry

Gene Alias

ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, TXGP1LOX40 antigen

Host Species

Mouse

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

NB100-64375 recognizes feline CD134, otherwise known as OX40, a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.

Target Species

Feline

Form

Purified

Related Products

Img

Novus Biologicals

NB10064375W

--

Img

Novus Biologicals

NB10064375Z

--

Img

Novus Biologicals

NB10064375G

--

Img

Novus Biologicals

NB10064375R

--

Img

Novus Biologicals

NB10064375P

--

Img

Novus Biologicals

NB10064375C

--

Img

Novus Biologicals

NB10064306W

--

Img

Novus Biologicals

NB10064306Y

--

Description

  • OX40/TNFRSF4 Monoclonal specifically detects OX40/TNFRSF4 in Feline samples
  • It is validated for Western Blot, Flow Cytometry, Product Image.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB10064375X

--


Antigen:
OX40/TNFRSF4

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
TNFRSF4

Immunogen:
CHO-derived feline CD134-Fc fusion protein.

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Immunology

Gene ID (Entrez):
7293

Reconstitution:
Protein A purified

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Applications:
Western Blot, Flow Cytometry

Clone:
7D6

Dilution:
Western Blot, Flow Cytometry

Gene Alias:
ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, TXGP1LOX40 antigen

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64375 recognizes feline CD134, otherwise known as OX40, a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.

Target Species:
Feline

Form:
Purified

Img

Novus Biologicals

NB10064375Z

--


Antigen:
OX40/TNFRSF4

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
TNFRSF4

Immunogen:
CHO-derived feline CD134-Fc fusion protein.

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Cycle and Replication, Immunology

Gene ID (Entrez):
7293

Reconstitution:
Protein A purified

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1

Applications:
Western Blot, Flow Cytometry

Clone:
7D6

Dilution:
Western Blot, Flow Cytometry

Gene Alias:
ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, TXGP1LOX40 antigen

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64375 recognizes feline CD134, otherwise known as OX40, a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.

Target Species:
Feline

Form:
Purified

Img

Fischer Scientific

NB10064378

--


Antigen:
FIV gp95

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
__

Immunogen:
Made to FIV gp95

Quantity:
0.125 mg

Research Discipline:
__

Gene ID (Entrez):
__

Reconstitution:
__

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1

Applications:
Western Blot, Flow Cytometry, Functional Assay

Clone:
SU1-30

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, Functional

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64378 specifically recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4.(3) Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains.(1) NB100-64378 does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies.

Target Species:
Virus

Form:
Purified

Img

Novus Biologicals

NB10064378C

--


Antigen:
FIV gp95

Classification:
Monoclonal

Conjugate:
DyLight 650

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
__

Immunogen:
Made to FIV gp95

Quantity:
0.125 mL

Research Discipline:
__

Gene ID (Entrez):
__

Reconstitution:
__

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG1

Applications:
Western Blot, Flow Cytometry

Clone:
SU1-30

Dilution:
Western Blot, Flow Cytometry

Gene Alias:
__

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
NB100-64378 specifically recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4.(3) Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains.(1) NB100-64378 does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies.

Target Species:
Virus

Form:
__