PD-L2/B7-DC/PDCD1LG2 Antibody (TY25) - BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
PD-L2/B7-DC/PDCD1LG2
Classification
Monoclonal
Concentration
1.0 mg/mL
Dilution
Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Symbols
PDCD1LG2
Immunogen
B7-DC transfected RAW264.7 cells.
Quantity
0.125 mg
Primary or Secondary
Primary
Test Specificity
NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG2a
Applications
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry (Frozen)
Clone
TY25
Conjugate
Unconjugated
Gene Alias
B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2
Host Species
Rat
Purification Method
Protein G purified
Regulatory Status
RUO
Gene ID (Entrez)
80380
Target Species
Mouse
Form
Purified
Related Products
Description
- PD-L2/B7-DC/PDCD1LG2 Monoclonal specifically detects PD-L2/B7-DC/PDCD1LG2 in Mouse samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Frozen.
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Antigen: PD-L2/B7-DC/PDCD1LG2
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Symbols: PDCD1LG2
Immunogen: B7-DC transfected RAW264.7 cells.
Quantity: 0.125 mg
Primary or Secondary: Primary
Test Specificity: NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2a
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry (Frozen)
Clone: TY25
Conjugate: Unconjugated
Gene Alias: B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 80380
Target Species: Mouse
Form: Purified
Antigen: CD31/PECAM-1
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Symbols: PECAM1
Immunogen: Porcine CD31/human IgGFc fusion protein
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: Recognizes porcine CD31, also known as Platelet endothelial cell adhesion molecule (PECAM-1).
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Frozen)
Clone: LCI-4
Conjugate: Unconjugated
Gene Alias: adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA', PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet/endothelial cell adhesion molecule
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5175
Target Species: Human, Porcine
Form: Purified
Antigen: CD31/PECAM-1
Classification: Monoclonal
Concentration: __
Dilution: Flow Cytometry
Gene Symbols: PECAM1
Immunogen: This CD31/PECAM-1 Antibody (LCI-4) was developed against porcine CD31/human IgG Fc fusion protein.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes porcine CD31, also known as Platelet endothelial cell adhesion molecule (PECAM-1).
Content And Storage: Store at 4C in the dark.
Isotype: IgG1
Applications: Flow Cytometry
Clone: LCI-4
Conjugate: APC
Gene Alias: adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5175
Target Species: Human, Porcine
Form: Purified