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NB10065388Z

L-Selectin/CD62L Antibody (FMC46), Alexa Fluor™ 700, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB10065388Z-Each-of-1 In Stock ₹ 52,191.60

NB10065388Z - Each of 1

₹ 52,191.60

In Stock

Quantity

1

Base Price: ₹ 52,191.60

GST (18%): ₹ 9,394.488

Total Price: ₹ 61,586.088

Antigen

L-Selectin/CD62L

Classification

Monoclonal

Conjugate

Alexa Fluor 700

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Alias

CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Content And Storage

Store at 4C in the dark.

Isotype

IgG2b

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

Clone

FMC46

Dilution

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Gene Accession No.

P14151

Gene Symbols

SELL

Immunogen

PHA stimulated lymphoblasts.

Quantity

0.1 mL

Research Discipline

Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells

Gene ID (Entrez)

6402

Target Species

Human, Bovine, Canine, Primate

Form

Purified

Description

  • Description L-Selectin/CD62L Monoclonal specifically detects L-Selectin/CD62L in Human, Bovine, Canine, Primate samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.

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Img

Novus Biologicals

NB10065388Z

--

Antigen:
L-Selectin/CD62L
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone:
FMC46
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Accession No.:
P14151
Gene Symbols:
SELL
Immunogen:
PHA stimulated lymphoblasts.
Quantity:
0.1 mL
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells
Gene ID (Entrez):
6402
Target Species:
Human, Bovine, Canine, Primate
Form:
Purified

Img

Fischer Scientific

NB10065391

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Antigen:
P-Selectin/CD62P
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Alias:
CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-65391 recognizes the P-Selectin cell surface antigen, a 140kD glycoprotein. P-Selectin is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry (Frozen)
Clone:
Psel.KO.2.12
Dilution:
Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.:
P16109
Gene Symbols:
SELP
Immunogen:
P-Selectin transfected 300.19 cells.
Quantity:
0.1 mg
Research Discipline:
__
Gene ID (Entrez):
6403
Target Species:
Human, Rat, Goat, Sheep
Form:
Purified

Img

Novus Biologicals

NB10065391C

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Antigen:
P-Selectin/CD62P
Classification:
Monoclonal
Conjugate:
DyLight 650
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Alias:
CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
NB100-65391 recognizes the P-Selectin cell surface antigen, a 140kD glycoprotein. P-Selectin is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells.
Content And Storage:
Store at 4°C in the dark.
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone:
Psel.KO.2.12
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Accession No.:
__
Gene Symbols:
SELP
Immunogen:
P-Selectin transfected 300.19 cells.
Quantity:
0.1 mL
Research Discipline:
__
Gene ID (Entrez):
6403.0
Target Species:
Human, Rat, Goat, Sheep
Form:
__

Img

Novus Biologicals

NB10065391J

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Antigen:
P-Selectin/CD62P
Classification:
Monoclonal
Conjugate:
APC
Formulation:
__
Gene Alias:
CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-65391 recognizes the P-Selectin cell surface antigen, a 140kD glycoprotein. P-Selectin is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
Psel.KO.2.12
Dilution:
Flow Cytometry
Gene Accession No.:
P16109
Gene Symbols:
SELP
Immunogen:
P-Selectin transfected 300.19 cells.
Quantity:
0.1 mL
Research Discipline:
__
Gene ID (Entrez):
6403
Target Species:
Human, Rat, Goat, Sheep
Form:
Purified