NB10065938Z
MHC Class I Antibody (2G5), Alexa Fluor™ 700, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB10065938Z-Each-of-1 | In Stock | ₹ 53,218.32 |
NB10065938Z - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,218.32
GST (18%): ₹ 9,579.298
Total Price: ₹ 62,797.618
Antigen
MHC Class I
Classification
Monoclonal
Conjugate
Alexa Fluor 700
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
HLA-E
Immunogen
Purified H-2Kb and H-2Db MHC-I molecules.
Quantity
0.125 mL
Research Discipline
Adaptive Immunity, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez)
3133
Target Species
Human, Mouse, Rat, Porcine, Bovine, Guinea Pig, Hamster, Sheep
Form
Purified
Applications
Flow Cytometry
Clone
2G5
Dilution
Flow Cytometry
Gene Alias
DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
NB100-65938 recognizes a monomorphic epitope on the mouse MHC class I antigen. The epitope recognized by clone 2G5 is conformation dependent and is reported to be phylogenetically conserved. Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class 1.
Content And Storage
Store at 4C in the dark.
Isotype
IgG2b
Description
- MHC Class I Monoclonal specifically detects MHC Class I in Human, Mouse, Rat, Porcine, Bovine, Chinese Hamster, Guinea Pig, Hamster, Sheep samples
- It is validated for Flow Cytometry.
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Antigen: MHC Class I
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: HLA-E
Immunogen: Purified H-2Kb and H-2Db MHC-I molecules.
Quantity: 0.125 mL
Research Discipline: Adaptive Immunity, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez): 3133
Target Species: Human, Mouse, Rat, Porcine, Bovine, Guinea Pig, Hamster, Sheep
Form: Purified
Applications: Flow Cytometry
Clone: 2G5
Dilution: Flow Cytometry
Gene Alias: DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-65938 recognizes a monomorphic epitope on the mouse MHC class I antigen. The epitope recognized by clone 2G5 is conformation dependent and is reported to be phylogenetically conserved. Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class 1.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b
Antigen:
MHC Class I
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
HLA-E
Immunogen:
Purified H-2Kb and H-2Db MHC-I molecules.
Quantity:
0.125 mL
Research Discipline:
Adaptive Immunity, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez):
3133
Target Species:
Human, Mouse, Rat, Porcine, Bovine, Guinea Pig, Hamster, Sheep
Form:
Purified
Applications:
Flow Cytometry
Clone:
2G5
Dilution:
Flow Cytometry
Gene Alias:
DKFZp686P19218, EA1.2, EA2.1, HLA class I histocompatibility antigen, alpha chain E, HLA class I histocompatibility antigen, E alpha chain, HLA-6.2, HLAE, lymphocyte antigen, major histocompatibility complex, class I, E, MHC, MHC class I antigen E, MHC HLA-E alpha-1, MHC HLA-E alpha-2.1, QA1
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-65938 recognizes a monomorphic epitope on the mouse MHC class I antigen. The epitope recognized by clone 2G5 is conformation dependent and is reported to be phylogenetically conserved. Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class 1.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b
Antigen: NKG2D/CD314
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: KLRK1
Immunogen: NKL cells.
Quantity: 0.25 mg
Research Discipline: __
Gene ID (Entrez): 22914
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), CyTOF, Functional Assay
Clone: 1D11
Dilution: Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready, Functional Assay
Gene Alias: CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Content And Storage: Store at -20C. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
NKG2D/CD314
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
KLRK1
Immunogen:
NKL cells.
Quantity:
0.25 mg
Research Discipline:
__
Gene ID (Entrez):
22914
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), CyTOF, Functional Assay
Clone:
1D11
Dilution:
Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready, Functional Assay
Gene Alias:
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Content And Storage:
Store at -20C. Avoid freeze-thaw cycles.
Isotype:
IgG1
Antigen: NKG2D/CD314
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: __
Gene Symbols: KLRK1
Immunogen: NKL cells.
Quantity: 0.25 mL
Research Discipline: __
Gene ID (Entrez): 22914
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: 1D11
Dilution: Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Content And Storage: Store at 4C in the dark.
Isotype: IgG1
Antigen:
NKG2D/CD314
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
__
Gene Symbols:
KLRK1
Immunogen:
NKL cells.
Quantity:
0.25 mL
Research Discipline:
__
Gene ID (Entrez):
22914
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
1D11
Dilution:
Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1
Antigen: NKG2D/CD314
Classification: Monoclonal
Conjugate: DyLight 755
Formulation: __
Gene Symbols: KLRK1
Immunogen: NKL cells.
Quantity: 0.25 mL
Research Discipline: __
Gene ID (Entrez): 22914
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: 1D11
Dilution: Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Content And Storage: Store at 4C in the dark.
Isotype: IgG1
Antigen:
NKG2D/CD314
Classification:
Monoclonal
Conjugate:
DyLight 755
Formulation:
__
Gene Symbols:
KLRK1
Immunogen:
NKL cells.
Quantity:
0.25 mL
Research Discipline:
__
Gene ID (Entrez):
22914
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
1D11
Dilution:
Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1