Integrin alpha 4/CD49d Antibody (HP2/1), DyLight 405, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB12022858V-Each-of-1 | In Stock | ₹ 52,191.60 |
NB12022858V - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,191.60
GST (18%): ₹ 9,394.488
Total Price: ₹ 61,586.088
Antigen
Integrin alpha 4/CD49d
Classification
Monoclonal
Conjugate
DyLight 405
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
ITGA4
Immunogen
JM leukaemia line (Human).
Quantity
0.1 mL
Research Discipline
Cancer, Cellular Markers, Cytoskeleton Markers, Phospho Specific
Gene ID (Entrez)
3676
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone
HP2/1
Dilution
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias
269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 1995). Mo
Content And Storage
Store at 4C in the dark.
Isotype
IgG1
Related Products
Description
- Description Integrin alpha 4/CD49d Monoclonal specifically detects Integrin alpha 4/CD49d in Human samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.
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Antigen: Integrin alpha 4/CD49d
Classification: Monoclonal
Conjugate: DyLight 405
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: ITGA4
Immunogen: JM leukaemia line (Human).
Quantity: 0.1 mL
Research Discipline: Cancer, Cellular Markers, Cytoskeleton Markers, Phospho Specific
Gene ID (Entrez): 3676
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: HP2/1
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias: 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 1995). Mo
Content And Storage: Store at 4C in the dark.
Isotype: IgG1
Antigen: ABO, Blood Group B Antigen
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: ABO
Immunogen: Mixture of erythrocytes of blood group B and glycoprotein fraction isolated from the saliva of secretors with blood group B.
Quantity: 1 mL
Research Discipline: __
Gene ID (Entrez): 28
Target Species: Human
Form: Supernatant
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Aggregation
Clone: HEB-29
Dilution: Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Aggregation
Gene Alias: A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT
Host Species: Mouse
Purification Method: Concentrated Supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The antibody HEB-29 reacts with human blood group B. The specifity of the antibody HEB-29 was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood.
Content And Storage: Store at 4C. Do not freeze.
Isotype: IgM
Antigen: RGS3
Classification: Polyclonal
Conjugate: Unconjugated
Formulation: PBS (pH 7.2), 1% BSA, 50% Glycerol with 0.02% Sodium Azide
Gene Symbols: RGS3
Immunogen: E. coli expressed human RGS 3 (amino acids 401-519).
Quantity: 0.1 mg
Research Discipline: Signal Transduction
Gene ID (Entrez): 5998
Target Species: Human
Form: __
Applications: Western Blot, Immunoprecipitation
Clone: __
Dilution: Western Blot, Immunoprecipitation
Gene Alias: C2PA, FLJ20370, FLJ31516, FLJ90496, PDZ-RGS3, regulator of G-protein signaling 3, regulator of G-protein signalling 3, RGP3
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Isotype: IgG
