NB247670PCP

HLA-DR Antibody (LN-3), PerCP, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB247670PCP-Each-of-1 In Stock ₹ 54,458.94

NB247670PCP - Each of 1

₹ 54,458.94

In Stock

Quantity

1

Base Price: ₹ 54,458.94

GST (18%): ₹ 9,802.609

Total Price: ₹ 64,261.549

Antigen

HLA-DR

Classification

Monoclonal

Conjugate

PerCP

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

HLA-DRA

Immunogen

Activated human peripheral blood mononuclear cells

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Content And Storage

Store at 4C in the dark.

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

LN-3

Dilution

Flow Cytometry

Gene Alias

FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez)

3122

Target Species

Human, Monkey, Mouse (Negative)

Form

Purified

Description

  • HLA-DR Monoclonal specifically detects HLA-DR in Human, Monkey, Mouse (Negative) samples
  • It is validated for Flow Cytometry.

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Novus Biologicals

NB247670PCP

--


Antigen:
HLA-DR

Classification:
Monoclonal

Conjugate:
PerCP

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
HLA-DRA

Immunogen:
Activated human peripheral blood mononuclear cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
LN-3

Dilution:
Flow Cytometry

Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez):
3122

Target Species:
Human, Monkey, Mouse (Negative)

Form:
Purified

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Novus Biologicals

NB247671

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Antigen:
Anillin

Classification:
Polyclonal

Conjugate:
Biotin

Formulation:
PBS

Gene Symbols:
__

Immunogen:
The immunogen recognized by this antibody maps to a region between residue 1074 and 1124 of human actin binding protein Anillin using the numbering given in entry NP_061155.2 (GeneID 54443).

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
__

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
actin-binding protein anillin, ANILLIN, anillin (Drosophila Scraps homolog), actin binding protein, anillin, actin binding protein, anillin, actin binding protein (scraps homolog, Drosophila), DKFZp779A055, Drosophila Scraps homolog, scra, Scraps

Host Species:
Rabbit

Purification Method:
Immunogen affinity purified

Research Discipline:
__

Gene ID (Entrez):
54443

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NB247672

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Antigen:
NIPBL

Classification:
Polyclonal

Conjugate:
DyLight 650

Formulation:
50mM Sodium Borate

Gene Symbols:
__

Immunogen:
The immunogen recognized by this antibody maps to a region between residue 1025 and 1075 of human Nipped-B-like using the numbering given in entry NP_597677.2 (GeneID 25836).

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG

Applications:
Western Blot

Clone:
__

Dilution:
Western Blot

Gene Alias:
CDLS1, delangin, DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, FLJ44854, IDN3-B, IDN3CDLS, Nipped-B homolog (Drosophila), nipped-B-like protein, Scc2, SCC2 homolog, sister chromatid cohesion 2 homolog

Host Species:
Rabbit

Purification Method:
Immunogen affinity purified

Research Discipline:
Cell Cycle and Replication

Gene ID (Entrez):
25836

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NB247672488

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Antigen:
HLA DRB1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
HLA-DRB1

Immunogen:
Activated human peripheral blood mononuclear cells (LN-3 and HLA-DRB/1067)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with the beta-chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
LN-3 + HLA-DRB/1067

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
Clone P2-beta-3, DR1, DR-1, DR12, DR-12, DR13, DR-13, DR14, DR-14, DR16, DR-16, DR4, DR-4, DR5, DR-5, DR7, DR-7, DR8, DR-8, DR9, DR-9, DRB1, DRw10, DRw11, DRw8, DW2.2/DR2.2, FLJ75017, FLJ76359, HLA class II antigen beta chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA-DR1B, HLA-DRB, HLA-DRB1*, HLA-DRB2, HLA-DR-beta 1, human leucocyte antigen DRB1, leucocyte antigen DR beta 1 chain, leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen DRB1*1, MHC class II antigen DRB1*10, MHC class II antigen DRB1*11, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*4, MHC class II antigen DRB1*7, MHC class II antigen DRB1*8, MHC class II antigen DRB1*9, MHC class II antigen HLA-DR13, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface gly

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Asthma, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
3123

Target Species:
Human, Monkey

Form:
Purified