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NB247773700

TTF-1/ NKX2-1 Antibody (8G7G3/1 + NX2.1/690), Alexa Fluor™ 700, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB247773700-Each-of-1 In Stock ₹ 55,271.76

NB247773700 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

TTF-1 / NKX2-1

Classification

Monoclonal

Conjugate

Alexa Fluor 700

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

NKX2-1

Immunogen

Rat full length TTF-1/ NKX2-1 recombinant protein (8G7G3/1); Recombinant TTF-1/ NKX2-1 protein (NX2.1/690) (Uniprot: P43699)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

8G7G3/1 + NX2.1/690

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias

benign chorea, Homeobox protein NK-2 homolog A, homeobox protein Nkx-2.1, NK2 homeobox 1, NK-2 homolog A, NKX2ANKX2.1, Thyroid nuclear factor 1, Thyroid transcription factor 1BHC, TITF1TEBP, TTF1, TTF1BCH, TTF-1NK-2

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Membrane Trafficking and Chaperones, Tumor Biomarkers

Gene ID (Entrez)

7080

Target Species

Human, Mouse, Rat

Form

Purified

Description

  • TTF-1 / NKX2-1 Monoclonal specifically detects TTF-1 / NKX2-1 in Human, Mouse, Rat samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

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Novus Biologicals

NB247773700

--

Antigen:
TTF-1 / NKX2-1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
NKX2-1
Immunogen:
Rat full length TTF-1/ NKX2-1 recombinant protein (8G7G3/1); Recombinant TTF-1/ NKX2-1 protein (NX2.1/690) (Uniprot: P43699)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
8G7G3/1 + NX2.1/690
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
benign chorea, Homeobox protein NK-2 homolog A, homeobox protein Nkx-2.1, NK2 homeobox 1, NK-2 homolog A, NKX2ANKX2.1, Thyroid nuclear factor 1, Thyroid transcription factor 1BHC, TITF1TEBP, TTF1, TTF1BCH, TTF-1NK-2
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Membrane Trafficking and Chaperones, Tumor Biomarkers
Gene ID (Entrez):
7080
Target Species:
Human, Mouse, Rat
Form:
Purified

Img

Novus Biologicals

NB247773PCP

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Antigen:
TTF-1 / NKX2-1
Classification:
Monoclonal
Conjugate:
PerCP
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
NKX2-1
Immunogen:
Rat full length TTF-1/ NKX2-1 recombinant protein (8G7G3/1); Recombinant TTF-1/ NKX2-1 protein (NX2.1/690) (Uniprot: P43699)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
8G7G3/1 + NX2.1/690
Dilution:
Flow Cytometry
Gene Alias:
benign chorea, Homeobox protein NK-2 homolog A, homeobox protein Nkx-2.1, NK2 homeobox 1, NK-2 homolog A, NKX2ANKX2.1, Thyroid nuclear factor 1, Thyroid transcription factor 1BHC, TITF1TEBP, TTF1, TTF1BCH, TTF-1NK-2
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Membrane Trafficking and Chaperones, Tumor Biomarkers
Gene ID (Entrez):
7080
Target Species:
Human, Mouse, Rat
Form:
Purified

Img

Novus Biologicals

NB247774

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Antigen:
KIF2C
Classification:
Polyclonal
Conjugate:
DyLight 680
Formulation:
50mM Sodium Borate
Gene Symbols:
__
Immunogen:
The immunogen recognized by this antibody maps to a region between residue 50 and 100 of mouse Mitotic Centromere-Associated Kinesin using the numbering given in entry NP_608301.2 (GeneID 73804 ).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
kinesin family member 2C, kinesin-like 6 (mitotic centromere-associated kinesin), Kinesin-like protein 6, kinesin-like protein KIF2C, MCAKKNSL6kinesin-like 6, Mitotic centromere-associated kinesin
Host Species:
Rabbit
Purification Method:
Immunogen affinity purified
Research Discipline:
Cancer, Cell Biology, Cellular Markers, DNA Repair
Gene ID (Entrez):
11004
Target Species:
Mouse
Form:
Purified

Img

Novus Biologicals

NB247775405

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Antigen:
ZAP70
Classification:
Monoclonal
Conjugate:
Alexa Fluor 405
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
ZAP70
Immunogen:
Recombinant full-length human ZAP70 protein (ZAP70/528); Recombinant ZAP-70 protein including residues 1-254 and encompassing SH2 domains of human ZAP70 (2F3.2) (Uniprot: P43403)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
ZAP70 is a 70kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well.Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
ZAP70/528 + 2F3.2
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
70 kDa zeta-associated protein, EC 2.7.10, EC 2.7.10.2, SRKFLJ17679, STDFLJ17670, Syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, TZK, ZAP-70, zeta-chain (TCR) associated protein kinase (70 kD), zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase, 70kD
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Cell Biology, Immunology, Phospho Specific, Protein Kinase, Signal Transduction, Tyrosine Kinases
Gene ID (Entrez):
7535
Target Species:
Human
Form:
Purified