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NB247897488

p21/CIP1/CDKN1A Antibody (CIP1/823 + DCS-60.2), Alexa Fluor™ 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB247897488-Each-of-1 In Stock ₹ 55,742.34

NB247897488 - Each of 1

₹ 55,742.34

In Stock

Quantity

1

Base Price: ₹ 55,742.34

GST (18%): ₹ 10,033.621

Total Price: ₹ 65,775.961

Antigen

p21/CIP1/CDKN1A

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

CDKN1A

Immunogen

Recombinant full-length human p21/CIP1/CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2) (Uniprot: P38936)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).

Content And Storage

Store at 4C in the dark.

Isotype

IgG2a κ

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

CIP1/823 + DCS-60.2

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Phospho Specific

Gene ID (Entrez)

1026

Target Species

Human, Mouse (Negative), Rat (Negative)

Form

Purified

Description

  • Description p21/CIP1/CDKN1A Monoclonal specifically detects p21/CIP1/CDKN1A in Human, Mouse (Negative), Rat (Negative) samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NB247897488

--

Antigen:
p21/CIP1/CDKN1A
Classification:
Monoclonal
Conjugate:
Alexa Fluor 488
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
CDKN1A
Immunogen:
Recombinant full-length human p21/CIP1/CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2) (Uniprot: P38936)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2a κ
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
CIP1/823 + DCS-60.2
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Phospho Specific
Gene ID (Entrez):
1026
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified

Img

Novus Biologicals

NB247897700

--

Antigen:
p21/CIP1/CDKN1A
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
CDKN1A
Immunogen:
Recombinant full-length human p21/CIP1/CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2) (Uniprot: P38936)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2a κ
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
CIP1/823 + DCS-60.2
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Phospho Specific
Gene ID (Entrez):
1026
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified

Img

Novus Biologicals

NB247899

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Antigen:
TRERF1
Classification:
Polyclonal
Conjugate:
Janelia Fluor 646
Formulation:
50mM Sodium Borate
Gene Symbols:
__
Immunogen:
The immunogen recognized by this antibody maps to a region between residue 1150 and 1200 of human transcriptional regulating protein 132 (transcriptional regulating factor 1) using the numbering given in entry NP_277037.1 (GeneID 55809).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
BCAR2, Breast cancer estrogen resistance 2RAPAHSA277276, dJ139D8.5, FLJ21198, rapa-1, rapa-2, RP1-139D8.5, transcriptional regulating factor 1, transcriptional regulating protein 132, transcriptional-regulating factor 1, Transcriptional-regulating protein 132, TReP-132, TREP132, Zinc finger protein rapa, Zinc finger transcription factor TReP-132
Host Species:
Rabbit
Purification Method:
Immunogen affinity purified
Research Discipline:
__
Gene ID (Entrez):
55809
Target Species:
Human
Form:
Purified

Img

Novus Biologicals

NB247900

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Antigen:
EEF2K
Classification:
Polyclonal
Conjugate:
DyLight 350
Formulation:
50mM Sodium Borate
Gene Symbols:
__
Immunogen:
The immunogen recognized by this antibody maps to a region between residue 675 and 725 of human calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase (EEF2K ) using the numbering given in entry NP_037434.1 (GeneID 29904).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase, EC 2.7.11, EC 2.7.11.20, eEF-2 kinase, eEF-2Kcalmodulin-dependent protein kinase III, elongation factor-2 kinase, eukaroytic elongation factor 2 kinase, eukaryotic elongation factor 2 kinase, eukaryotic elongation factor-2 kinase, HSU93850, MGC45041
Host Species:
Rabbit
Purification Method:
Immunogen affinity purified
Research Discipline:
Cancer, Hypoxia Signaling, Phospho Specific
Gene ID (Entrez):
29904
Target Species:
Human, Mouse
Form:
Purified