NB254308200
Prostatic Acid Phosphatase/ACPP Antibody (ACPP/1338) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
Prostatic Acid Phosphatase/ACPP
Classification
Monoclonal
Concentration
1 mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias
acid phosphatase, prostate, ACP3, ACP-3, EC 3.1.3.2, PAP, prostatic acid phosphatase, prostatic acid phosphotase
Host Species
Mouse
Molecular Weight of Antigen
52 kDa
Quantity
200 μg
Research Discipline
Cell Cycle and Replication
Gene ID (Entrez)
55
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Clone
ACPP/1338
Conjugate
Unconjugated
Formulation
PBS with No Preservative
Gene Symbols
ACPP
Immunogen
Recombinant human ACPP fragment
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
Content And Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- Prostatic Acid Phosphatase/ACPP Monoclonal specifically detects Prostatic Acid Phosphatase/ACPP in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Prostatic Acid Phosphatase/ACPP
Classification: Monoclonal
Concentration: 1 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias: acid phosphatase, prostate, ACP3, ACP-3, EC 3.1.3.2, PAP, prostatic acid phosphatase, prostatic acid phosphotase
Host Species: Mouse
Molecular Weight of Antigen: 52 kDa
Quantity: 200 μg
Research Discipline: Cell Cycle and Replication
Gene ID (Entrez): 55
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Clone: ACPP/1338
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Gene Symbols: ACPP
Immunogen: Recombinant human ACPP fragment
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype: IgG1 κ
Antigen:
Prostatic Acid Phosphatase/ACPP
Classification:
Monoclonal
Concentration:
1 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias:
acid phosphatase, prostate, ACP3, ACP-3, EC 3.1.3.2, PAP, prostatic acid phosphatase, prostatic acid phosphotase
Host Species:
Mouse
Molecular Weight of Antigen:
52 kDa
Quantity:
200 μg
Research Discipline:
Cell Cycle and Replication
Gene ID (Entrez):
55
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Clone:
ACPP/1338
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Gene Symbols:
ACPP
Immunogen:
Recombinant human ACPP fragment
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype:
IgG1 κ
Antigen: Jak2
Classification: Polyclonal
Concentration: __
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: EC 2.7.10, EC 2.7.10.2, JAK-2, Janus kinase 2Janus kinase 2 (a protein tyrosine kinase), JTK10, tyrosine-protein kinase JAK2
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 0.1 mL
Research Discipline: Cell Cycle and Replication, Phospho Specific, Signal Transduction
Gene ID (Entrez): 3717
Target Species: Human
Form: Purified
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: __
Conjugate: Alexa Fluor 750
Formulation: 50mM Sodium Borate
Gene Symbols: __
Immunogen: The immunogen recognized by this antibody maps to a region between residue 1082 and 1132 of human Janus kinase 2 using the numbering given in entry NP_004963.1 (GeneID 3717).
Purification Method: Immunogen affinity purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4°C in the dark.
Isotype: IgG
Antigen:
Jak2
Classification:
Polyclonal
Concentration:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
EC 2.7.10, EC 2.7.10.2, JAK-2, Janus kinase 2Janus kinase 2 (a protein tyrosine kinase), JTK10, tyrosine-protein kinase JAK2
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Research Discipline:
Cell Cycle and Replication, Phospho Specific, Signal Transduction
Gene ID (Entrez):
3717
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Conjugate:
Alexa Fluor 750
Formulation:
50mM Sodium Borate
Gene Symbols:
__
Immunogen:
The immunogen recognized by this antibody maps to a region between residue 1082 and 1132 of human Janus kinase 2 using the numbering given in entry NP_004963.1 (GeneID 3717).
Purification Method:
Immunogen affinity purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark.
Isotype:
IgG
Antigen: MAML3
Classification: Monoclonal
Concentration: 1 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias: CAG/CTG 3, ERDA3, MAM-2, mam-3, mastermind-like 3 (Drosophila), mastermind-like protein 3, polyglutamine rich, trinucleotide repeat containing 3
Host Species: Mouse
Molecular Weight of Antigen: 160 kDa
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): 55534
Target Species: Human
Form: __
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Clone: MAML3/1303
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Gene Symbols: MAML3
Immunogen: Recombinant human MAML3 protein fragment
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: MAML3 (mastermind-like protein 3) is a nuclear speckle protein that acts as a transcriptional coactivator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAML3 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, MAML3 interacts with the ankyrin repeats of the Notch proteins Notch 1, Notch 2, Notch 3 and Notch 4. This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-Jk; a complex that can then induce HES1 gene expression. While the N-terminal domain of MAML3 is essential for proper Notch binding, the C-terminal domain of MAML3 is essential for transcriptional activation. Due to its involvement in cell signaling and transcriptional activation, upregulation of MAML3 is thought to be involved in oncogenesis.
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
MAML3
Classification:
Monoclonal
Concentration:
1 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias:
CAG/CTG 3, ERDA3, MAM-2, mam-3, mastermind-like 3 (Drosophila), mastermind-like protein 3, polyglutamine rich, trinucleotide repeat containing 3
Host Species:
Mouse
Molecular Weight of Antigen:
160 kDa
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
55534
Target Species:
Human
Form:
__
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Clone:
MAML3/1303
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Gene Symbols:
MAML3
Immunogen:
Recombinant human MAML3 protein fragment
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
MAML3 (mastermind-like protein 3) is a nuclear speckle protein that acts as a transcriptional coactivator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAML3 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, MAML3 interacts with the ankyrin repeats of the Notch proteins Notch 1, Notch 2, Notch 3 and Notch 4. This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-Jk; a complex that can then induce HES1 gene expression. While the N-terminal domain of MAML3 is essential for proper Notch binding, the C-terminal domain of MAML3 is essential for transcriptional activation. Due to its involvement in cell signaling and transcriptional activation, upregulation of MAML3 is thought to be involved in oncogenesis.
Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype:
IgG1
Antigen: MAML3
Classification: Monoclonal
Concentration: 1 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias: CAG/CTG 3, ERDA3, MAM-2, mam-3, mastermind-like 3 (Drosophila), mastermind-like protein 3, polyglutamine rich, trinucleotide repeat containing 3
Host Species: Mouse
Molecular Weight of Antigen: 160 kDa
Quantity: 200 μg
Research Discipline: Neuroscience
Gene ID (Entrez): 55534
Target Species: Human
Form: __
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Clone: MAML3/1303
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Gene Symbols: MAML3
Immunogen: Recombinant human MAML3 protein fragment
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: MAML3 (mastermind-like protein 3) is a nuclear speckle protein that acts as a transcriptional coactivator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAML3 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, MAML3 interacts with the ankyrin repeats of the Notch proteins Notch 1, Notch 2, Notch 3 and Notch 4. This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-Jk; a complex that can then induce HES1 gene expression. While the N-terminal domain of MAML3 is essential for proper Notch binding, the C-terminal domain of MAML3 is essential for transcriptional activation. Due to its involvement in cell signaling and transcriptional activation, upregulation of MAML3 is thought to be involved in oncogenesis.
Content And Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
MAML3
Classification:
Monoclonal
Concentration:
1 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias:
CAG/CTG 3, ERDA3, MAM-2, mam-3, mastermind-like 3 (Drosophila), mastermind-like protein 3, polyglutamine rich, trinucleotide repeat containing 3
Host Species:
Mouse
Molecular Weight of Antigen:
160 kDa
Quantity:
200 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
55534
Target Species:
Human
Form:
__
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), CyTOF
Clone:
MAML3/1303
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Gene Symbols:
MAML3
Immunogen:
Recombinant human MAML3 protein fragment
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
MAML3 (mastermind-like protein 3) is a nuclear speckle protein that acts as a transcriptional coactivator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAML3 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, MAML3 interacts with the ankyrin repeats of the Notch proteins Notch 1, Notch 2, Notch 3 and Notch 4. This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-Jk; a complex that can then induce HES1 gene expression. While the N-terminal domain of MAML3 is essential for proper Notch binding, the C-terminal domain of MAML3 is essential for transcriptional activation. Due to its involvement in cell signaling and transcriptional activation, upregulation of MAML3 is thought to be involved in oncogenesis.
Content And Storage:
Store at -20 to -80C. Avoid freeze-thaw cycles.
Isotype:
IgG1