NB279354

Fas/TNFRSF6/CD95 Antibody (R-125224), mFluor Violet 500 SE, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB279354-Each-of-1 In Stock ₹ 46,801.32

NB279354 - Each of 1

₹ 46,801.32

In Stock

Quantity

1

Base Price: ₹ 46,801.32

GST (18%): ₹ 8,424.238

Total Price: ₹ 55,225.558

Antigen

Fas/TNFRSF6/CD95

Classification

Monoclonal

Conjugate

mFluor Violet 500 SE

Formulation

50mM Sodium Borate

Host Species

Rabbit

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

Flow Cytometry

Clone

R-125224

Dilution

Flow Cytometry

Gene Alias

Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6

Immunogen

R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells

Gene ID (Entrez)

355

Content And Storage

Store at 4C in the dark.

Isotype

IgG κ

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Description

  • Fas/TNFRSF6/CD95 Monoclonal antibody specifically detects Fas/TNFRSF6/CD95 in Human samples
  • It is validated for Flow Cytometry

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB279354

--


Antigen:
Fas/TNFRSF6/CD95

Classification:
Monoclonal

Conjugate:
mFluor Violet 500 SE

Formulation:
50mM Sodium Borate

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
R-125224

Dilution:
Flow Cytometry

Gene Alias:
Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6

Immunogen:
R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells

Gene ID (Entrez):
355

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG κ

Img

Novus Biologicals

NB279356

--


Antigen:
CD45RB

Classification:
Monoclonal

Conjugate:
mFluor Violet 450 SE

Formulation:
50mM Sodium Borate

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
rPTPRC/1132

Dilution:
Flow Cytometry

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Immunogen:
Recombinant full-length human CD45RB protein (Uniprot: P08575)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Microglia Markers, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
5788

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NB279359

--


Antigen:
B7-2/CD86

Classification:
Monoclonal

Conjugate:
mFluor Violet 450 SE

Formulation:
50mM Sodium Borate

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Flow Cytometry

Clone:
C86/1146

Dilution:
Flow Cytometry, Flow (Cell Surface)

Gene Alias:
Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86

Immunogen:
Recombinant human full-length B7-2/CD86 protein (Uniprot: P42081)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology, Inflammation, Myeloid derived Suppressor Cell, Signal Transduction

Gene ID (Entrez):
942

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NB279360

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Antigen:
TOP1MT

Classification:
Monoclonal

Conjugate:
mFluor Violet 450 SE

Formulation:
50mM Sodium Borate

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
rTOP1MT/488

Dilution:
Flow Cytometry

Gene Alias:
mitochondrial, mitochondrial DNA topoisomerase I, topoisomerase (DNA) I, mitochondrial

Immunogen:
Recombinant full-length human TOP1MT protein (Uniprot: Q969P6 )

Quantity:
0.1 mL

Research Discipline:
Cancer

Gene ID (Entrez):
116447

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ