NB281830

Fas/TNFRSF6/CD95 Antibody (R-125224), mFluor Violet 610 SE, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB281830-Each-of-1 In Stock ₹ 48,555.30

NB281830 - Each of 1

₹ 48,555.30

In Stock

Quantity

1

Base Price: ₹ 48,555.30

GST (18%): ₹ 8,739.954

Total Price: ₹ 57,295.254

Antigen

Fas/TNFRSF6/CD95

Classification

Monoclonal

Conjugate

mFluor Violet 610 SE

Formulation

50mM Sodium Borate

Host Species

Rabbit

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

Flow Cytometry

Clone

R-125224

Dilution

Flow Cytometry

Gene Alias

Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6

Immunogen

R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells

Gene ID (Entrez)

355

Content And Storage

Store at 4C in the dark.

Isotype

IgG κ

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Description

  • Fas/TNFRSF6/CD95 Monoclonal antibody specifically detects Fas/TNFRSF6/CD95 in Human samples
  • It is validated for Flow Cytometry

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB281830

--


Antigen:
Fas/TNFRSF6/CD95

Classification:
Monoclonal

Conjugate:
mFluor Violet 610 SE

Formulation:
50mM Sodium Borate

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
R-125224

Dilution:
Flow Cytometry

Gene Alias:
Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6

Immunogen:
R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells

Gene ID (Entrez):
355

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG κ

Img

Novus Biologicals

NB281832

--


Antigen:
PEDFR/PNPLA2/ATGL

Classification:
Monoclonal

Conjugate:
mFluor Violet 610 SE

Formulation:
50mM Sodium Borate

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
AT18E6

Dilution:
Flow Cytometry

Gene Alias:
Adipose triglyceride lipase, ATGL1110001C14Rik, Calcium-independent phospholipase A2, Desnutrin, EC 3.1.1.3, FP17548, IPLA2-zeta, patatin-like phospholipase domain containing 2, patatin-like phospholipase domain-containing protein 2, patatin-like phospholipase domain-containing protein 2-like, PEDF-R, Pigment epithelium-derived factor, Transport-secretion protein 2, transport-secretion protein 2.2, triglyceride hydrolase, TTS2.2, TTS-2.2, TTS2DKFZp667M109

Immunogen:
Recombinant human PEDFR/PNPLA2/ATGL (30-504aa) purified from E. coli

Quantity:
0.1 mL

Research Discipline:
Autophagy, Cancer, Diabetes Research, Lipid and Metabolism, Lipid Droplets, Signal Transduction

Gene ID (Entrez):
57104

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

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Novus Biologicals

NB281833

--


Antigen:
KIR2DL1/CD158a

Classification:
Monoclonal

Conjugate:
mFluor Violet 610 SE

Formulation:
50mM Sodium Borate

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
2F9

Dilution:
Flow Cytometry

Gene Alias:
CD158 antigen-like family member A, CD158a antigen, CD158Ankat1, cl-42, killer cell immunoglobulin-like receptor 2DL1, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1, killer Ig receptor, killer inhibitory receptor 2-2-1, KIR221, MHC class I NK cell receptor, Natural killer-associated transcript 1, NKAT, NKAT-1, NKAT1KIR-K64, p58 killer cell inhibitory receptor KIR-K64, p58 natural killer cell receptor clones CL-42/47.11, p58 NK cell inhibitory receptor NKR-K6,47.11, p58 NK receptor CL-42/47.11, p58.1, p58.1 MHC class-I-specific NK receptor

Immunogen:
Recombinant human KIR2DL1/CD158a (23-223 aa) purified from E. coli

Quantity:
0.1 mL

Research Discipline:
Immunology, Innate Immunity, Signal Transduction

Gene ID (Entrez):
3802

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a κ

Img

Novus Biologicals

NB281840

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Antigen:
Rac1,2,3

Classification:
Monoclonal

Conjugate:
mFluor Violet 450 SE

Formulation:
50mM Sodium Borate

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry

Clone:
AT2G10

Dilution:
Flow Cytometry

Gene Alias:
AI323801;AI452260;AL023026;D5Ertd559e;EN-7;Gx;HSPC022;MIG5;p21-Rac1;p21-Rac2;RAC1;Rac-1;Rac1B;RAC2;RAC3;TC25;TC-25

Immunogen:
Recombinant human Rac1,2,3 (1-189aa) protein purified from E. coli

Quantity:
0.1 mL

Research Discipline:
B Cell Development and Differentiation Markers, Cancer, Cell Biology, Cytoskeleton Markers, GPCR, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Protein Phosphatase, Signal Transduction

Gene ID (Entrez):
__

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ