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NB281986

Fas/TNFRSF6/CD95 Antibody (R-125224), mFluor Violet 610 SE, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB281986-Each-of-1 In Stock ₹ 48,555.30

NB281986 - Each of 1

₹ 48,555.30

In Stock

Quantity

1

Base Price: ₹ 48,555.30

GST (18%): ₹ 8,739.954

Total Price: ₹ 57,295.254

Antigen

Fas/TNFRSF6/CD95

Classification

Monoclonal

Conjugate

mFluor Violet 610 SE

Formulation

50mM Sodium Borate

Host Species

Human

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

Flow Cytometry

Clone

R-125224

Dilution

Flow Cytometry

Gene Alias

Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6

Immunogen

R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells

Gene ID (Entrez)

355

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

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Description

  • Fas/TNFRSF6/CD95 Monoclonal antibody specifically detects Fas/TNFRSF6/CD95 in Human samples
  • It is validated for Flow Cytometry

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB281986

--

Antigen:
Fas/TNFRSF6/CD95
Classification:
Monoclonal
Conjugate:
mFluor Violet 610 SE
Formulation:
50mM Sodium Borate
Host Species:
Human
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry
Clone:
R-125224
Dilution:
Flow Cytometry
Gene Alias:
Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6
Immunogen:
R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells
Gene ID (Entrez):
355
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ

Img

Novus Biologicals

NB281992

--

Antigen:
CD45
Classification:
Monoclonal
Conjugate:
mFluor Violet 450 SE
Formulation:
50mM Sodium Borate
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry
Clone:
SPM570
Dilution:
Flow Cytometry
Gene Alias:
B220, CD_antigen: CD45, CD45, CD45 antigen, CD45R, EC 3.1.3.48, EC:3.1.3.48, GP180, LCA, L-CA, Leukocyte common antigen, LY5, protein tyrosine phosphatase, receptor type, c polypeptide, PTPRC, receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen
Immunogen:
Isolated neoplastic cells from T cell lymphoma
Quantity:
0.1 mL
Research Discipline:
Adaptive Immunity, Autoimmune Diseases, Cell Biology, Cellular Markers, Cellular Signaling, Cytokine Research, Glia Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Inflammation, Innate Immunity, MAP Kinase Signaling, Mast Cell Markers, Mesenchymal Stem Cell Markers, Microglia Markers, Modulation of DNA Pools, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
5788
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ

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Novus Biologicals

NB281995

--

Antigen:
C10orf82
Classification:
Monoclonal
Conjugate:
mFluor Violet 500 SE
Formulation:
50mM Sodium Borate
Host Species:
Mouse
Purification Method:
Immunogen affinity purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry
Clone:
OTI1G4
Dilution:
Flow Cytometry
Gene Alias:
chromosome 10 open reading frame 82, Em:AC016825.4, FLJ40268, hypothetical protein LOC143379, MGC33547
Immunogen:
Full length human recombinant protein of human C10orf82 (NP_653262) produced in HEK293T cell.
Quantity:
0.1 mL
Research Discipline:
__
Gene ID (Entrez):
143379
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1

Img

Novus Biologicals

NB281997

--

Antigen:
RFC2
Classification:
Monoclonal
Conjugate:
mFluor Violet 500 SE
Formulation:
50mM Sodium Borate
Host Species:
Mouse
Purification Method:
Immunogen affinity purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Flow Cytometry
Clone:
OTI11C6
Dilution:
Flow Cytometry
Gene Alias:
A1, A1 40 kDa subunit, Activator 1 40 kDa subunit, Activator 1 subunit 2, MGC3665, replication factor C (activator 1) 2, 40kDa, replication factor C 2, Replication factor C 40 kDa subunit, replication factor C subunit 2, RF-C 40 kDa subunit, RFC40replication factor C (activator 1) 2 (40kD)
Immunogen:
Full length human recombinant protein of human RFC2(NP_002905) produced in E.coli.
Quantity:
0.1 mL
Research Discipline:
Cell Cycle and Replication, DNA Repair
Gene ID (Entrez):
5982
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1