Fas/TNFRSF6/CD95 Antibody (R-125224), mFluor Violet 500 SE, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB282448-Each-of-1 | In Stock | ₹ 46,801.32 |
NB282448 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,801.32
GST (18%): ₹ 8,424.238
Total Price: ₹ 55,225.558
Antigen
Fas/TNFRSF6/CD95
Classification
Monoclonal
Conjugate
mFluor Violet 500 SE
Formulation
50mM Sodium Borate
Host Species
Human
Purification Method
Protein A purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Flow Cytometry
Clone
R-125224
Dilution
Flow Cytometry
Gene Alias
Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6
Immunogen
R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.
Quantity
0.1 mL
Research Discipline
Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells
Gene ID (Entrez)
355
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Description
- Fas/TNFRSF6/CD95 Monoclonal antibody specifically detects Fas/TNFRSF6/CD95 in Human samples
- It is validated for Flow Cytometry
Compare Similar Items
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Antigen: Fas/TNFRSF6/CD95
Classification: Monoclonal
Conjugate: mFluor Violet 500 SE
Formulation: 50mM Sodium Borate
Host Species: Human
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Flow Cytometry
Clone: R-125224
Dilution: Flow Cytometry
Gene Alias: Apo-1 antigen, apoptosis antigen 1, Apoptosis-mediating surface antigen FAS, APT1FASTM, CD95 antigen, CD95ALPS1A, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas antigen, FAS1, FASLG receptor, TNFRSF6member 6, tumor necrosis factor receptor superfamily member 6
Immunogen: R-125224 is generated by the humanization of the murine HFE7A anti-Fas/TNFRSF6/CD95 antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas/TNFRSF6/CD95 antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas/TNFRSF6/CD95 or the L5178YA1 cell line expressing murine Fas/TNFRSF6/CD95, but not to the parental WR19L or L5178Y cells.
Quantity: 0.1 mL
Research Discipline: Apoptosis, Cancer, Cell Biology, Death Receptor Signaling Pathway, Diabetes Research, Hematopoietic Stem Cell Markers, Immunology, Inhibitors Activators and Regulators, Innate Immunity, Signal Transduction, Stem Cells
Gene ID (Entrez): 355
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen: PMEL17/SILV
Classification: Monoclonal
Conjugate: mFluor Violet 450 SE
Formulation: 50mM Sodium Borate
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Canine (Negative), Rat (Negative)
Form: Purified
Applications: Flow Cytometry
Clone: HMB45
Dilution: Flow Cytometry, Flow (Intracellular)
Gene Alias: D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Immunogen: Extract of pigmented melanoma metastases from lymph nodes
Quantity: 0.1 mL
Research Discipline: __
Gene ID (Entrez): 6490
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen: Integrin alpha 4/CD49d
Classification: Monoclonal
Conjugate: mFluor Violet 450 SE
Formulation: 50mM Sodium Borate
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Flow Cytometry
Clone: 7.2
Dilution: Flow Cytometry
Gene Alias: 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Immunogen: Human melanoma line DX3
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Biology, Cellular Markers, Cytokine Research, Growth and Development, Lysosome Markers, Mast Cell Markers, Membrane Trafficking and Chaperones, Microautophagy, Neuronal Cell Markers, Phospho Specific
Gene ID (Entrez): 3676
Content And Storage: Store at 4C in the dark.
Isotype: IgG1