NBP14089401
P2X7/P2RX7 Antibody (Hano43) - BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP14089401-Each-of-1 | In Stock | ₹ 42,737.22 |
NBP14089401 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,737.22
GST (18%): ₹ 7,692.70
Total Price: ₹ 50,429.92
Antigen
P2X7/P2RX7
Classification
Monoclonal
Concentration
1 mg/mL
Dilution
Flow Cytometry 1:25-1:200, Immunocytochemistry/Immunofluorescence 1:10-1:2000
Gene Accession No.
Q9Z1M0
Gene Symbols
P2RX7
Immunogen
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity
0.1 mg
Primary or Secondary
Primary
Test Specificity
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG2b
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone
Hano43
Conjugate
Unconjugated
Formulation
PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species
Rat
Purification Method
Protein G purified
Regulatory Status
RUO
Gene ID (Entrez)
5027
Target Species
Mouse
Form
Purified
Related Products
Description
- Description P2X7/P2RX7 Monoclonal specifically detects P2X7/P2RX7 in Mouse samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
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Show Difference
Antigen: P2X7/P2RX7
Classification: Monoclonal
Concentration: 1 mg/mL
Dilution: Flow Cytometry 1:25-1:200, Immunocytochemistry/Immunofluorescence 1:10-1:2000
Gene Accession No.: Q9Z1M0
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Conjugate: Unconjugated
Formulation: PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5027
Target Species: Mouse
Form: Purified
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Concentration:
1 mg/mL
Dilution:
Flow Cytometry 1:25-1:200, Immunocytochemistry/Immunofluorescence 1:10-1:2000
Gene Accession No.:
Q9Z1M0
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
Hano43
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5027
Target Species:
Mouse
Form:
Purified
Antigen: P2X7/P2RX7
Classification: Monoclonal
Concentration: __
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Accession No.: __
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Conjugate: DyLight 680
Formulation: __
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5027
Target Species: Mouse
Form: Purified
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Concentration:
__
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Accession No.:
__
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
Hano43
Conjugate:
DyLight 680
Formulation:
__
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5027
Target Species:
Mouse
Form:
Purified
Antigen: P2X7/P2RX7
Classification: Monoclonal
Concentration: __
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Accession No.: __
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Conjugate: DyLight 755
Formulation: __
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5027
Target Species: Mouse
Form: Purified
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Concentration:
__
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Accession No.:
__
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
Hano43
Conjugate:
DyLight 755
Formulation:
__
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5027
Target Species:
Mouse
Form:
Purified
Antigen: P2X7/P2RX7
Classification: Monoclonal
Concentration: __
Dilution: Flow Cytometry
Gene Accession No.: __
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b
Applications: Flow Cytometry
Clone: Hano43
Conjugate: PE
Formulation: __
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5027
Target Species: Mouse
Form: Purified
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Concentration:
__
Dilution:
Flow Cytometry
Gene Accession No.:
__
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
Hano43
Conjugate:
PE
Formulation:
__
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5027
Target Species:
Mouse
Form:
Purified