P2X7/P2RX7 Antibody (Hano43), Alexa Fluor™ 488, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP140894X-Each-of-1 | In Stock | ₹ 53,218.32 |
NBP140894X - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,218.32
GST (18%): ₹ 9,579.298
Total Price: ₹ 62,797.618
Antigen
P2X7/P2RX7
Classification
Monoclonal
Conjugate
Alexa Fluor 488
Gene Alias
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species
Rat
Purification Method
Protein G purified
Regulatory Status
RUO
Gene ID (Entrez)
5027
Target Species
Mouse
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone
Hano43
Dilution
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Symbols
P2RX7
Immunogen
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage
Store at 4C in the dark.
Isotype
IgG2b
Related Products
Description
- Description P2X7/P2RX7 Monoclonal specifically detects P2X7/P2RX7 in Mouse samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
Compare Similar Items
Show Difference
Antigen: P2X7/P2RX7
Classification: Monoclonal
Conjugate: Alexa Fluor 488
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5027
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b
Antigen: P2X7/P2RX7
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 5027
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b
Antigen: TREM1
Classification: Monoclonal
Conjugate: PerCP
Gene Alias: CD354 antigen, TREM-1Triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 54210
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone: L5-B8.2A12.3A12
Dilution: Flow Cytometry
Gene Symbols: TREM1
Immunogen: Mouse TREM-1 Fc fusion protein.
Quantity: 0.25 mL
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4C in the dark.
Isotype: IgG2a