Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NBP142151-Each-of-1 | In Stock | ₹ 51,934.92 |
NBP142151 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,934.92
GST (18%): ₹ 9,348.286
Total Price: ₹ 61,283.206
CD42b/GPIb alpha
Monoclonal
LYOPH
Immunocytochemistry/Immunofluorescence 1:10-1:2000, In vivo assay
GP1BA
The antibody reacts with the CD42b antigen.
0.2 mg
Immunology
2811
Reconstitute with 1 ml sterile water.
Store at 4C. Do not freeze.
IgG1 κ
Immunocytochemistry, Immunofluorescence, In vitro Assay
VM16d
Unconjugated
Antigen CD42b-alpha, BSS, CD42b, CD42b antigen, CD42b-alpha, glycoprotein Ib (platelet), alpha polypeptide, Glycoprotein Ibalpha, GP1B, GP-Ib alpha, GPIbA, GPIb-alpha, MGC34595, platelet glycoprotein Ib alpha chain, platelet membrane glycoprotein 1b-alpha subunit
Mouse
Ammonium sulfate precipitation
RUO
Primary
The monoclonal antibody is directed against the CD42b antigen, platelet glycoprotein GPIb, that serves as a receptor for von Willebrand factor and as a high affinity thrombin receptor. The antigen is expressed on human platelets and megakaryocytes. The antigen is absent or present in very low levels on platelets of patients with the Bernard-Soulier syndrome. VM16d inhibits low conc. thrombin (<0.1 U/ml) induced platelet aggregation and decreases thrombin binding to platelets. F (ab') 2 and F (ab') fragments are equally effective as whole intact antibodies. The VM16d-epitope is located within the 45 kDa N-terminal domain of GPIb alpha- chain. VM16d does not effect platelet interaction with von Willebrand factor, leading to the conclu-sion that the antibody reacts with or nearby the thrombin receptor site.
Human
Precipitation