NBP142343

MRP6 Antibody (M6II-31), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP142343-Each-of-1 In Stock ₹ 31,999.44

NBP142343 - Each of 1

₹ 31,999.44

In Stock

Quantity

1

Base Price: ₹ 31,999.44

GST (18%): ₹ 5,759.899

Total Price: ₹ 37,759.339

Antigen

MRP6

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Tissue culture supernatant with 0.1% Sodium Azide

Gene Symbols

ABCC6

Immunogen

Fusion protein containing amino acids 764 to 964 of human MRP6 (FP M6II).

Quantity

0.2 mL

Research Discipline

Cancer

Gene ID (Entrez)

368

Target Species

Human

Form

Supernatant

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

M6II-31

Dilution

Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias

Anthracycline resistance-associated protein, ARAPXE, ATP-binding cassette, sub-family C (CFTR/MRP), member 6, EST349056, MLP1ABC34, MOATE, MOAT-E, MRP6ATP-binding cassette sub-family C member 6, multidrug resistance-associated protein 6, Multi-specific organic anion transporter E, pseudoxanthoma elasticum, PXE1, URG7

Host Species

Rat

Purification Method

Tissue culture supernatant

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

M6II-31 reacts with MRP6, a 190-200 kD transmembrane protein that is related to the multidrug resistance related protein MRP. Mutations in the MRP6 gene are responsible for the connective tissue disorder Pseudoxanthoma elasticum (PXE). M6II-31 was raised against a bacterial fusion protein of human MRP6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein. M6II-7 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MRP4, MRP5 gene products.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG2a

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Description

  • MRP6 Monoclonal specifically detects MRP6 in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

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Show Difference

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Novus Biologicals

NBP142343

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Antigen:
MRP6

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Tissue culture supernatant with 0.1% Sodium Azide

Gene Symbols:
ABCC6

Immunogen:
Fusion protein containing amino acids 764 to 964 of human MRP6 (FP M6II).

Quantity:
0.2 mL

Research Discipline:
Cancer

Gene ID (Entrez):
368

Target Species:
Human

Form:
Supernatant

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
M6II-31

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
Anthracycline resistance-associated protein, ARAPXE, ATP-binding cassette, sub-family C (CFTR/MRP), member 6, EST349056, MLP1ABC34, MOATE, MOAT-E, MRP6ATP-binding cassette sub-family C member 6, multidrug resistance-associated protein 6, Multi-specific organic anion transporter E, pseudoxanthoma elasticum, PXE1, URG7

Host Species:
Rat

Purification Method:
Tissue culture supernatant

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
M6II-31 reacts with MRP6, a 190-200 kD transmembrane protein that is related to the multidrug resistance related protein MRP. Mutations in the MRP6 gene are responsible for the connective tissue disorder Pseudoxanthoma elasticum (PXE). M6II-31 was raised against a bacterial fusion protein of human MRP6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein. M6II-7 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MRP4, MRP5 gene products.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

Img

Novus Biologicals

NBP142348

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Antigen:
MRP3

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
1 ml serum-free tissue culture supernatant with 0.25 mg/ml immunoglobulin and 0.7% BSA with 0.1% Sodium Azide

Gene Symbols:
ABCC3

Immunogen:
The antibody reacts with the MRP3 antigen.

Quantity:
0.2 mL

Research Discipline:
__

Gene ID (Entrez):
8714

Target Species:
Human

Form:
Supernatant

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
M3II-21

Dilution:
Western Blot 1:20-1:50, Simple Western, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:20, Immunocytochemistry/Immunofluorescence 1:20-1:50, Immunohistochemistry-Frozen 1:20

Gene Alias:
ABC31, ATP-binding cassette sub-family C member 3, ATP-binding cassette, sub-family C (CFTR/MRP), member 3, canalicular multispecific organic anion transporter 2, canicular multispecific organic anion transporter, cMOAT2, EC 3.6.3, EC 3.6.3.44, EC 6.3.2.4, MLP2DKFZp686E22157, MRP3MOAT-DEST90757, multidrug resistance associated protein, Multidrug resistance-associated protein 3, Multi-specific organic anion transporter D

Host Species:
Mouse

Purification Method:
Tissue culture supernatant

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
M3II-21 reacts with an internal epitope of MRP3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. M3II-21 was raised against a bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein. M3II-21 does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2b

Img

Novus Biologicals

NBP142349

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Antigen:
MRP2

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
ABCC2

Immunogen:
The antibody reacts with the MRP2 antigen.

Quantity:
0.2 mL

Research Discipline:
ABC Transporters, Amino Acids Drugs and other small molecules, Cancer, Diabetes Research, Lipid and Metabolism

Gene ID (Entrez):
1244

Target Species:
Human, Rat

Form:
Supernatant

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
M2III-6

Dilution:
Western Blot 1:20-1:50, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:20-1:50, Immunohistochemistry-Paraffin 1:20, Immunohistochemistry-Frozen 1:20

Gene Alias:
ATP-binding cassette, sub-family C (CFTR/MRP), member 2, Canalicular multidrug resistance protein, canalicular multispecific organic anion transporter 1, CMOAT1, CMOATABC30, CMRP, DJS, KIAA1010, MRP2ATP-binding cassette sub-family C member 2, Multidrug resistance-associated protein 2

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
M2III-6 reacts with an internal epitope of cMOAT/MRP2, a 170-180 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. cMOAT/MRP2 is closely related to the multidrug resistance related protein MRP, and cMOAT/MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2III-6 was raised against a bacterial fusion protein of cMOAB/MRP2, containing the 202-amino acid COOH terminal end of the protein. M2III-6 did not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

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NBP142360

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Antigen:
CCL2/MCP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
CCL2

Immunogen:
The antibody reacts with both human natural and recombinant MCP1 in ELISA.

Quantity:
0.2 mL

Research Discipline:
Apoptosis, Cancer, Chemokine Research, Cytokine Research, Hypoxia, Immunology, Innate Immunity, Signal Transduction

Gene ID (Entrez):
6347

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation

Clone:
MNA1

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, Immunoassay, Blocking/Neutralizing 50-200 molar excess

Gene Alias:
C-C motif chemokine 2, chemokine (C-C motif) ligand 2, GDCF-2, HC11Monocyte secretory protein JE, MCAFMonocyte chemotactic and activating factor, MCP1 Monocyte chemotactic protein 1, MCP-1 Small-inducible cytokine A2, MGC9434, Monocyte chemoattractant protein 1, monocyte chemoattractant protein-1, SCYA2HSMCR30, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je), small inducible cytokine subfamily A (Cys-Cys), member 2, SMC-CF

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
The antibody reacts with both human natural and recombinant MCP1 in ELISA. MCP1 is a member of the CC subfamily of chemokines. MCP1 is a proinflammatory cytokine which acts both as an activation factor and as chemokine for monocytic cells. The antibody inhibits the biological activity of natural and recombinant human MCP1. The antigen specificity was assessed by ELISA. The antigen specificity was further assessed by immunoprecipitation and western blot. No crossreactivities with other cytokines have been detected.

Content And Storage:
Store at 4C. Do not freeze.

Isotype:
IgG1