NBP232855B
PMEL17/SILV Mouse, Clone: SPM286, Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
PMEL17/SILV
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias
D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Host Species
Mouse
Purification Method
Protein A purified
Regulatory Status
RUO
Gene ID (Entrez)
6490
Target Species
Human, Equine, Rat (Negative)
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone
SPM286
Dilution
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Gene Accession No.
P40967
Gene Symbols
PMEL
Immunogen
Membranes from a human melanoma metastasis
Quantity
0.2 mg
Primary or Secondary
Primary
Test Specificity
By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage
Store at 4C.
Isotype
IgG2b κ
Description
- PMEL17/SILV Monoclonal specifically detects PMEL17/SILV in Human, Equine, Rat (Negative) samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
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Antigen: PMEL17/SILV
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Gene ID (Entrez): 6490
Target Species: Human, Equine, Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: SPM286
Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Gene Accession No.: P40967
Gene Symbols: PMEL
Immunogen: Membranes from a human melanoma metastasis
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage: Store at 4C.
Isotype: IgG2b κ
Antigen:
PMEL17/SILV
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias:
D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
6490
Target Species:
Human, Equine, Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM286
Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Gene Accession No.:
P40967
Gene Symbols:
PMEL
Immunogen:
Membranes from a human melanoma metastasis
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage:
Store at 4C.
Isotype:
IgG2b κ
Antigen: PMEL17/SILV
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Gene ID (Entrez): 6490
Target Species: Human, Equine, Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: SPM286
Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Gene Accession No.: P40967
Gene Symbols: PMEL
Immunogen: Membranes from a human melanoma metastasis
Quantity: 0.02 mg
Primary or Secondary: Primary
Test Specificity: By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage: Store at 4C.
Isotype: IgG2b κ
Antigen:
PMEL17/SILV
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias:
D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
6490
Target Species:
Human, Equine, Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM286
Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Gene Accession No.:
P40967
Gene Symbols:
PMEL
Immunogen:
Membranes from a human melanoma metastasis
Quantity:
0.02 mg
Primary or Secondary:
Primary
Test Specificity:
By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage:
Store at 4C.
Isotype:
IgG2b κ
Antigen: CCL16/HCC-4/LEC
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Gene ID (Entrez): 6360
Target Species: Human
Form: Purified
Applications: ELISA, Functional Assay, SDS-Page
Clone: LEC66
Dilution: ELISA, Functional, SDS-Page
Gene Accession No.: O15467
Gene Symbols: CCL16
Immunogen: Recombinant human HCC-4 protein
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CCL16/HCC-4/LEC
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias:
C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
6360
Target Species:
Human
Form:
Purified
Applications:
ELISA, Functional Assay, SDS-Page
Clone:
LEC66
Dilution:
ELISA, Functional, SDS-Page
Gene Accession No.:
O15467
Gene Symbols:
CCL16
Immunogen:
Recombinant human HCC-4 protein
Quantity:
0.1 mg
Primary or Secondary:
Primary
Test Specificity:
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CCL16/HCC-4/LEC
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias: C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Gene ID (Entrez): 6360
Target Species: Human
Form: Purified
Applications: ELISA, Functional Assay, SDS-Page
Clone: LEC66
Dilution: ELISA, Functional, SDS-Page
Gene Accession No.: O15467
Gene Symbols: CCL16
Immunogen: Recombinant human HCC-4 protein
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CCL16/HCC-4/LEC
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias:
C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
6360
Target Species:
Human
Form:
Purified
Applications:
ELISA, Functional Assay, SDS-Page
Clone:
LEC66
Dilution:
ELISA, Functional, SDS-Page
Gene Accession No.:
O15467
Gene Symbols:
CCL16
Immunogen:
Recombinant human HCC-4 protein
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ