NBP233094X

MAGE 1 Antibody (MA454), Alexa Fluor™ 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP233094X-Each-of-1 In Stock ₹ 55,271.76

NBP233094X - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

MAGE 1

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Gene Alias

Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, member 1, CT1.1melanoma antigen family A 1, MAGE-1 antigen, MAGE1A, MAGE1melanoma antigen MAGE-1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E), melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, MGC9326

Host Species

Mouse

Molecular Weight of Antigen

44 kDa

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Melanoma Cell Markers, Tumor Suppressors

Gene ID (Entrez)

4100

Target Species

Human, Rat, Canine

Form

Purified

Applications

ELISA

Clone

MA454

Dilution

ELISA

Gene Symbols

MAGEA1

Immunogen

Recombinant full-length human MAGE 1 protein (Uniprot: P43355)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 42-46kDa, identified as MAGE-1. This monoclonal antibody does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • MAGE 1 Monoclonal specifically detects MAGE 1 in Human, Rat, Canine samples
  • It is validated for ELISA.

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Novus Biologicals

NBP233094X

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Antigen:
MAGE 1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Alias:
Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, member 1, CT1.1melanoma antigen family A 1, MAGE-1 antigen, MAGE1A, MAGE1melanoma antigen MAGE-1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E), melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, MGC9326

Host Species:
Mouse

Molecular Weight of Antigen:
44 kDa

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Melanoma Cell Markers, Tumor Suppressors

Gene ID (Entrez):
4100

Target Species:
Human, Rat, Canine

Form:
Purified

Applications:
ELISA

Clone:
MA454

Dilution:
ELISA

Gene Symbols:
MAGEA1

Immunogen:
Recombinant full-length human MAGE 1 protein (Uniprot: P43355)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 42-46kDa, identified as MAGE-1. This monoclonal antibody does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233096B

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Antigen:
Thyroglobulin

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
AITD3TGN, TDH3, Tg, thyroglobulin

Host Species:
Mouse

Molecular Weight of Antigen:
660 kDa

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology

Gene ID (Entrez):
7038

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
60

Dilution:
Western Blot, Immunohistochemistry-Paraffin

Gene Symbols:
TG

Immunogen:
Thyroglobulin isolated from human thyroid glands was used as the immunogen for the antibody.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233096C

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Antigen:
Thyroglobulin

Classification:
Monoclonal

Conjugate:
DyLight 650

Gene Alias:
AITD3TGN, TDH3, Tg, thyroglobulin

Host Species:
Mouse

Molecular Weight of Antigen:
660 kDa

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology

Gene ID (Entrez):
7038

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
60

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin

Gene Symbols:
TG

Immunogen:
Thyroglobulin isolated from human thyroid glands was used as the immunogen for the antibody.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233096G

--


Antigen:
Thyroglobulin

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
AITD3TGN, TDH3, Tg, thyroglobulin

Host Species:
Mouse

Molecular Weight of Antigen:
660 kDa

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology

Gene ID (Entrez):
7038

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
60

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin

Gene Symbols:
TG

Immunogen:
Thyroglobulin isolated from human thyroid glands was used as the immunogen for the antibody.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ