NBP233126

Uroplakin III Antibody - BSA Free, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP233126-Each-of-1 In Stock ₹ 46,886.88

NBP233126 - Each of 1

₹ 46,886.88

In Stock

Quantity

1

Base Price: ₹ 46,886.88

GST (18%): ₹ 8,439.638

Total Price: ₹ 55,326.518

Antigen

Uroplakin III

Classification

Polyclonal

Conjugate

Unconjugated

Formulation

10 mM PBS with 0.05% Sodium Azide

Gene Symbols

UPK3A

Immunogen

A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin III (Uniprot: O75631)

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG

Applications

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, CyTOF

Concentration

1.0 mg/mL

Dilution

Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, CyTOF-ready

Gene Alias

MGC119178, UP3a, UPIII, UPIIIA, UPK3, UPK3A, uroplakin 3, uroplakin 3A, Uroplakin III, uroplakin3a, uroplakin-3a

Host Species

Rabbit

Molecular Weight of Antigen

30 kDa

Quantity

0.1 mg

Research Discipline

Cancer

Gene ID (Entrez)

7380

Target Species

Human

Form

Purified

Description

  • Uroplakin III Polyclonal specifically detects Uroplakin III in Human samples
  • It is validated for Western Blot.

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Novus Biologicals

NBP233126

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Antigen:
Uroplakin III

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
10 mM PBS with 0.05% Sodium Azide

Gene Symbols:
UPK3A

Immunogen:
A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin III (Uniprot: O75631)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, CyTOF

Concentration:
1.0 mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, CyTOF-ready

Gene Alias:
MGC119178, UP3a, UPIII, UPIIIA, UPK3, UPK3A, uroplakin 3, uroplakin 3A, Uroplakin III, uroplakin3a, uroplakin-3a

Host Species:
Rabbit

Molecular Weight of Antigen:
30 kDa

Quantity:
0.1 mg

Research Discipline:
Cancer

Gene ID (Entrez):
7380

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP233128C

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
DyLight 650

Formulation:
__

Gene Symbols:
__

Immunogen:
Purified TAG-72 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Concentration:
__

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Host Species:
Mouse

Molecular Weight of Antigen:
220 kDa

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine

Form:
Purified

Img

Novus Biologicals

NBP233128FR

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
DyLight 680

Formulation:
__

Gene Symbols:
__

Immunogen:
Purified TAG-72 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Concentration:
__

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Host Species:
Mouse

Molecular Weight of Antigen:
220 kDa

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine

Form:
Purified

Img

Novus Biologicals

NBP233128IR

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
DyLight 755

Formulation:
__

Gene Symbols:
__

Immunogen:
Purified TAG-72 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Concentration:
__

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Host Species:
Mouse

Molecular Weight of Antigen:
220 kDa

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine

Form:
Purified