NBP233130X

UCH-L1/PGP9.5 Antibody (31A3), Alexa Fluor™ 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP233130X-Each-of-1 In Stock ₹ 55,271.76

NBP233130X - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

UCH-L1/PGP9.5

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Gene Alias

EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Host Species

Mouse

Molecular Weight of Antigen

25 kDa

Quantity

0.1 mL

Research Discipline

Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission

Gene ID (Entrez)

7345

Target Species

Human, Mouse, Rat, Porcine, Bovine

Form

Purified

Applications

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

31A3

Dilution

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Symbols

UCHL1

Immunogen

UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • UCH-L1/PGP9.5 Monoclonal specifically detects UCH-L1/PGP9.5 in Human, Mouse, Rat, Porcine, Bovine, Zebrafish samples
  • It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

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Img

Novus Biologicals

NBP233130X

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Antigen:
UCH-L1/PGP9.5

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Host Species:
Mouse

Molecular Weight of Antigen:
25 kDa

Quantity:
0.1 mL

Research Discipline:
Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission

Gene ID (Entrez):
7345

Target Species:
Human, Mouse, Rat, Porcine, Bovine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
31A3

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Symbols:
UCHL1

Immunogen:
UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233132B

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
CD56, CD56 NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez):
4684

Target Species:
Human, Rat, Zebrafish

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
123C3.D5

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Symbols:
NCAM1

Immunogen:
Membrane preparation of a small cell lung carcinoma.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233132C

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Conjugate:
DyLight 650

Gene Alias:
CD56, CD56 NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez):
4684

Target Species:
Human, Rat, Zebrafish

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
123C3.D5

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Symbols:
NCAM1

Immunogen:
Membrane preparation of a small cell lung carcinoma.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233132G

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
CD56, CD56 NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez):
4684

Target Species:
Human, Rat, Zebrafish

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
123C3.D5

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Symbols:
NCAM1

Immunogen:
Membrane preparation of a small cell lung carcinoma.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ